Breaking an Epigenetic Chromatin Switch: Curious Features of Hysteresis in Saccharomyces cerevisiae Telomeric Silencing

In addition to gene network switches, local epigenetic modifications to DNA and histones play an important role in all-or-none cellular decision-making. Here, we study the dynamical design of a well-characterized epigenetic chromatin switch: the yeast SIR system, in order to understand the origin of...

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Detalles Bibliográficos
Autores principales: Nagaraj, Vijayalakshmi H., Mukhopadhyay, Swagatam, Dayarian, Adel, Sengupta, Anirvan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275178/
https://www.ncbi.nlm.nih.gov/pubmed/25536038
http://dx.doi.org/10.1371/journal.pone.0113516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275178/
https://www.ncbi.nlm.nih.gov/pubmed/25536038
http://dx.doi.org/10.1371/journal.pone.0113516

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