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Pharmacokinetic Correlates of the Effects of a Heroin Vaccine on Heroin Self-Administration in Rats

The purpose of this study was to evaluate the effects of a morphine-conjugate vaccine (M-KLH) on the acquisition, maintenance, and reinstatement of heroin self-administration (HSA) in rats, and on heroin and metabolite distribution during heroin administration that approximated the self-administered...

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Detalles Bibliográficos
Autores principales: Raleigh, Michael D., Pentel, Paul R., LeSage, Mark G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275252/
https://www.ncbi.nlm.nih.gov/pubmed/25536404
http://dx.doi.org/10.1371/journal.pone.0115696