PHLDA1 Expression is Controlled by an Estrogen Receptor (ER)-NFκB-miR-181 Regulatory Loop and is Essential for Formation of ER+ Mammospheres

Crosstalk between estrogen receptor (ER) and the inflammatory nuclear factor κB (NFκB) pathway in ER+ breast cancers may contribute to a more aggressive phenotype. PHLDA1 (Pleckstrin Homology-Like Domain, Family A, member 1), one target gene of ER-NFκB crosstalk, has been implicated in cell survival...

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Detalles Bibliográficos
Autores principales: Kastrati, Irida, Canestrari, Emanuele, Frasor, Jonna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275416/
https://www.ncbi.nlm.nih.gov/pubmed/24954507
http://dx.doi.org/10.1038/onc.2014.180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275416/
https://www.ncbi.nlm.nih.gov/pubmed/24954507
http://dx.doi.org/10.1038/onc.2014.180

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