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Transcription mediated insulation and interference direct gene cluster expression switches

In yeast, many tandemly arranged genes show peak expression in different phases of the metabolic cycle (YMC) or in different carbon sources, indicative of regulation by a bi-modal switch, but it is not clear how these switches are controlled. Using native elongating transcript analysis (NET-seq), we...

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Detalles Bibliográficos
Autores principales:	Nguyen, Tania, Fischl, Harry, Howe, Françoise S, Woloszczuk, Ronja, Serra Barros, Ana, Xu, Zhenyu, Brown, David, Murray, Struan C, Haenni, Simon, Halstead, James M, O'Connor, Leigh, Shipkovenska, Gergana, Steinmetz, Lars M, Mellor, Jane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Computational and Systems Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275577/ https://www.ncbi.nlm.nih.gov/pubmed/25407679 http://dx.doi.org/10.7554/eLife.03635

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