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Control of membrane gaps by synaptotagmin-Ca(2+) measured with a novel membrane distance ruler
Fast synchronous neurotransmitter release is triggered by calcium that activates synaptotagmin-1 (syt-1), resulting in fusion of synaptic vesicles with the presynaptic membrane. Syt-1 possesses two Ca(2+)-binding C2 domains that tether membranes via interactions with anionic phospholipids. It is cap...
Autores principales: | Lin, Chao-Chen, Seikowski, Jan, Pérez-Lara, Angel, Jahn, Reinhard, Höbartner, Claudia, Walla, Peter Jomo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275583/ https://www.ncbi.nlm.nih.gov/pubmed/25500905 http://dx.doi.org/10.1038/ncomms6859 |
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