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The structural basis for receptor recognition of human interleukin-18
Interleukin (IL)-18 is a proinflammatory cytokine that belongs to the IL-1 family and plays an important role in inflammation. The uncontrolled release of this cytokine is associated with severe chronic inflammatory disease. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ)...
Autores principales: | Tsutsumi, Naotaka, Kimura, Takeshi, Arita, Kyohei, Ariyoshi, Mariko, Ohnishi, Hidenori, Yamamoto, Takahiro, Zuo, Xiaobing, Maenaka, Katsumi, Park, Enoch Y., Kondo, Naomi, Shirakawa, Masahiro, Tochio, Hidehito, Kato, Zenichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275594/ https://www.ncbi.nlm.nih.gov/pubmed/25500532 http://dx.doi.org/10.1038/ncomms6340 |
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