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Case report of rare chronic myelogenous leukemia related multibacterial splenic abscess presenting with scrotal swelling

INTRODUCTION: Splenic abscesses associated with leukemia are rare. Most reported cases of splenic abscesses occur after chemotherapy and are related to the immunosuppressive effects of the chemotherapy. Their etiology is most frequently fungal. PRESENTATION OF CASE: A 58-year-old male presented with...

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Autores principales: McPhillips, Sean, Friese, Randall, Vercruysse, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275781/
https://www.ncbi.nlm.nih.gov/pubmed/25460444
http://dx.doi.org/10.1016/j.ijscr.2014.10.069
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author McPhillips, Sean
Friese, Randall
Vercruysse, Gary
author_facet McPhillips, Sean
Friese, Randall
Vercruysse, Gary
author_sort McPhillips, Sean
collection PubMed
description INTRODUCTION: Splenic abscesses associated with leukemia are rare. Most reported cases of splenic abscesses occur after chemotherapy and are related to the immunosuppressive effects of the chemotherapy. Their etiology is most frequently fungal. PRESENTATION OF CASE: A 58-year-old male presented with splenomegaly and scrotal swelling secondary to a multibacterial splenic abscess which required a splenectomy. Upon investigation he was found to suffer from chronic myeloid leukemia (CML) and epididymitis. DISCUSSION: Splenic abscesses are rarely found in leukemic patients. Reported cases are fungal and commonly occur after chemotherapy due to immunosuppression. Scrotal swelling with concurrent splenomegaly can be found in other pathologies including brucellosis, Lyme disease and even non-Hodgkin primary testicular lymphoma. Scrotal swelling in our case was likely secondary to epididymitis and exacerbated by the effects of splenomegaly upon the systemic circulation promoting venous congestion. CONCLUSION: This case illustrated an unusual presentation of CML because the patient presented with splenomegaly, a multibacterial splenic abscess, and scrotal swelling.
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spelling pubmed-42757812014-12-28 Case report of rare chronic myelogenous leukemia related multibacterial splenic abscess presenting with scrotal swelling McPhillips, Sean Friese, Randall Vercruysse, Gary Int J Surg Case Rep Article INTRODUCTION: Splenic abscesses associated with leukemia are rare. Most reported cases of splenic abscesses occur after chemotherapy and are related to the immunosuppressive effects of the chemotherapy. Their etiology is most frequently fungal. PRESENTATION OF CASE: A 58-year-old male presented with splenomegaly and scrotal swelling secondary to a multibacterial splenic abscess which required a splenectomy. Upon investigation he was found to suffer from chronic myeloid leukemia (CML) and epididymitis. DISCUSSION: Splenic abscesses are rarely found in leukemic patients. Reported cases are fungal and commonly occur after chemotherapy due to immunosuppression. Scrotal swelling with concurrent splenomegaly can be found in other pathologies including brucellosis, Lyme disease and even non-Hodgkin primary testicular lymphoma. Scrotal swelling in our case was likely secondary to epididymitis and exacerbated by the effects of splenomegaly upon the systemic circulation promoting venous congestion. CONCLUSION: This case illustrated an unusual presentation of CML because the patient presented with splenomegaly, a multibacterial splenic abscess, and scrotal swelling. Elsevier 2014-10-23 /pmc/articles/PMC4275781/ /pubmed/25460444 http://dx.doi.org/10.1016/j.ijscr.2014.10.069 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Article
McPhillips, Sean
Friese, Randall
Vercruysse, Gary
Case report of rare chronic myelogenous leukemia related multibacterial splenic abscess presenting with scrotal swelling
title Case report of rare chronic myelogenous leukemia related multibacterial splenic abscess presenting with scrotal swelling
title_full Case report of rare chronic myelogenous leukemia related multibacterial splenic abscess presenting with scrotal swelling
title_fullStr Case report of rare chronic myelogenous leukemia related multibacterial splenic abscess presenting with scrotal swelling
title_full_unstemmed Case report of rare chronic myelogenous leukemia related multibacterial splenic abscess presenting with scrotal swelling
title_short Case report of rare chronic myelogenous leukemia related multibacterial splenic abscess presenting with scrotal swelling
title_sort case report of rare chronic myelogenous leukemia related multibacterial splenic abscess presenting with scrotal swelling
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275781/
https://www.ncbi.nlm.nih.gov/pubmed/25460444
http://dx.doi.org/10.1016/j.ijscr.2014.10.069
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