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Cardiac metastases and tumor embolization: A rare sequelae of primary undifferentiated liver sarcoma

INTRODUCTION: Primary hepatic sarcomas are uncommon malignant neoplasms; prognostic features, natural history, and optimal management of these tumors are not well characterized. PRESENTATION OF CASE: This report describes the management of a 51-year-old patient that underwent a right trisectionectom...

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Autores principales: Dua, Monica M., Cloyd, Jordan M., Haddad, Francois, Beygui, Ramin E., Norton, Jeffrey A., Visser, Brendan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275788/
https://www.ncbi.nlm.nih.gov/pubmed/25460438
http://dx.doi.org/10.1016/j.ijscr.2014.10.004
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author Dua, Monica M.
Cloyd, Jordan M.
Haddad, Francois
Beygui, Ramin E.
Norton, Jeffrey A.
Visser, Brendan C.
author_facet Dua, Monica M.
Cloyd, Jordan M.
Haddad, Francois
Beygui, Ramin E.
Norton, Jeffrey A.
Visser, Brendan C.
author_sort Dua, Monica M.
collection PubMed
description INTRODUCTION: Primary hepatic sarcomas are uncommon malignant neoplasms; prognostic features, natural history, and optimal management of these tumors are not well characterized. PRESENTATION OF CASE: This report describes the management of a 51-year-old patient that underwent a right trisectionectomy for a large hepatic mass found to be a liver sarcoma on pathology. He subsequently developed tumor emboli to his lungs and was discovered to have cardiac intracavitary metastases from his primary tumor. The patient underwent cardiopulmonary bypass and resection of the right-sided heart metastases to prevent further pulmonary sequela of tumor embolization. DISCUSSION: The lack of distinguishing symptoms or imaging characteristics that clearly define hepatic sarcomas makes it challenging to achieve a diagnosis prior to pathologic examination. Metastatic spread is frequently to the lung or pleura, but very rarely seen within the heart. Failure to recognize cardiac metastatic disease will ultimately lead to progressive tumor embolization and cardiac failure if left untreated. CONCLUSION: The most effective therapy for primary liver sarcomas is surgery; radical resection should be performed if possible given the aggressive nature of these tumors to progress and metastasize.
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spelling pubmed-42757882014-12-28 Cardiac metastases and tumor embolization: A rare sequelae of primary undifferentiated liver sarcoma Dua, Monica M. Cloyd, Jordan M. Haddad, Francois Beygui, Ramin E. Norton, Jeffrey A. Visser, Brendan C. Int J Surg Case Rep Article INTRODUCTION: Primary hepatic sarcomas are uncommon malignant neoplasms; prognostic features, natural history, and optimal management of these tumors are not well characterized. PRESENTATION OF CASE: This report describes the management of a 51-year-old patient that underwent a right trisectionectomy for a large hepatic mass found to be a liver sarcoma on pathology. He subsequently developed tumor emboli to his lungs and was discovered to have cardiac intracavitary metastases from his primary tumor. The patient underwent cardiopulmonary bypass and resection of the right-sided heart metastases to prevent further pulmonary sequela of tumor embolization. DISCUSSION: The lack of distinguishing symptoms or imaging characteristics that clearly define hepatic sarcomas makes it challenging to achieve a diagnosis prior to pathologic examination. Metastatic spread is frequently to the lung or pleura, but very rarely seen within the heart. Failure to recognize cardiac metastatic disease will ultimately lead to progressive tumor embolization and cardiac failure if left untreated. CONCLUSION: The most effective therapy for primary liver sarcomas is surgery; radical resection should be performed if possible given the aggressive nature of these tumors to progress and metastasize. Elsevier 2014-10-16 /pmc/articles/PMC4275788/ /pubmed/25460438 http://dx.doi.org/10.1016/j.ijscr.2014.10.004 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Article
Dua, Monica M.
Cloyd, Jordan M.
Haddad, Francois
Beygui, Ramin E.
Norton, Jeffrey A.
Visser, Brendan C.
Cardiac metastases and tumor embolization: A rare sequelae of primary undifferentiated liver sarcoma
title Cardiac metastases and tumor embolization: A rare sequelae of primary undifferentiated liver sarcoma
title_full Cardiac metastases and tumor embolization: A rare sequelae of primary undifferentiated liver sarcoma
title_fullStr Cardiac metastases and tumor embolization: A rare sequelae of primary undifferentiated liver sarcoma
title_full_unstemmed Cardiac metastases and tumor embolization: A rare sequelae of primary undifferentiated liver sarcoma
title_short Cardiac metastases and tumor embolization: A rare sequelae of primary undifferentiated liver sarcoma
title_sort cardiac metastases and tumor embolization: a rare sequelae of primary undifferentiated liver sarcoma
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275788/
https://www.ncbi.nlm.nih.gov/pubmed/25460438
http://dx.doi.org/10.1016/j.ijscr.2014.10.004
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