Cargando…

Giant retroperitoneal leiomyosarcoma. Multiorgan block removal

INTRODUCTION: Retroperitoneal tumors are rare, mostly malignant. Locally aggressive, and more frequent in women in their 5th decade of life. Its symptoms are nonspecific, including abdominal pain and palpable mass. To diagnosis is helpful computed tomography and biopsy. It needs surgery for absolute...

Descripción completa

Detalles Bibliográficos
Autores principales: Mateo Vallejo, F., Dominguez Reinado, M.R., Medina Achirica, C., Diaz Oteros, M., Esteban Ramos, J.L., Melero Brenes, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275809/
https://www.ncbi.nlm.nih.gov/pubmed/25460472
http://dx.doi.org/10.1016/j.ijscr.2014.10.061
_version_ 1782350180743380992
author Mateo Vallejo, F.
Dominguez Reinado, M.R.
Medina Achirica, C.
Diaz Oteros, M.
Esteban Ramos, J.L.
Melero Brenes, S.
author_facet Mateo Vallejo, F.
Dominguez Reinado, M.R.
Medina Achirica, C.
Diaz Oteros, M.
Esteban Ramos, J.L.
Melero Brenes, S.
author_sort Mateo Vallejo, F.
collection PubMed
description INTRODUCTION: Retroperitoneal tumors are rare, mostly malignant. Locally aggressive, and more frequent in women in their 5th decade of life. Its symptoms are nonspecific, including abdominal pain and palpable mass. To diagnosis is helpful computed tomography and biopsy. It needs surgery for absolute healing. PRESENTATION OF CASE: 67 years old man was admitted with back pain and fever. Abdominal imaging tests showed a 15 cm abdominal mass without clear organodependencia. Endoscopy with biopsies evidenced mesenchymal neoplasia of undetermined origin. In surgery we confirm its resecability and was necessary multiorgan resection. Pathologic diagnosis: well differentiated retroperitoneal leiomyosarcoma. Started adjuvant radiotherapy. In subsequent tests showed the presence of liver metastases. DISCUSSION: Retroperitoneal tumors are developed from nerve, vascular, muscular, connective, supportive and fibroareolar tissue from this space. Its size does not modificate survival or resectability. We used TC and biopsy for its diagnose. Adjuvant therapy does not affect survival or quality of life, surgery remains the only curative option. Locoregional recurrence is the most influential figure in the prognosis. A large percentage of patients required a second surgery (between 45 and 82%). CONCLUSION: The only curative option of retroperitoneal sarcomas is surgery, which usually requires multiple organ resection. Chemotherapy and radiotherapy are mostly a surgical supplement. Chemotherapy has not shown significant increase in survival.
format Online
Article
Text
id pubmed-4275809
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-42758092014-12-28 Giant retroperitoneal leiomyosarcoma. Multiorgan block removal Mateo Vallejo, F. Dominguez Reinado, M.R. Medina Achirica, C. Diaz Oteros, M. Esteban Ramos, J.L. Melero Brenes, S. Int J Surg Case Rep Article INTRODUCTION: Retroperitoneal tumors are rare, mostly malignant. Locally aggressive, and more frequent in women in their 5th decade of life. Its symptoms are nonspecific, including abdominal pain and palpable mass. To diagnosis is helpful computed tomography and biopsy. It needs surgery for absolute healing. PRESENTATION OF CASE: 67 years old man was admitted with back pain and fever. Abdominal imaging tests showed a 15 cm abdominal mass without clear organodependencia. Endoscopy with biopsies evidenced mesenchymal neoplasia of undetermined origin. In surgery we confirm its resecability and was necessary multiorgan resection. Pathologic diagnosis: well differentiated retroperitoneal leiomyosarcoma. Started adjuvant radiotherapy. In subsequent tests showed the presence of liver metastases. DISCUSSION: Retroperitoneal tumors are developed from nerve, vascular, muscular, connective, supportive and fibroareolar tissue from this space. Its size does not modificate survival or resectability. We used TC and biopsy for its diagnose. Adjuvant therapy does not affect survival or quality of life, surgery remains the only curative option. Locoregional recurrence is the most influential figure in the prognosis. A large percentage of patients required a second surgery (between 45 and 82%). CONCLUSION: The only curative option of retroperitoneal sarcomas is surgery, which usually requires multiple organ resection. Chemotherapy and radiotherapy are mostly a surgical supplement. Chemotherapy has not shown significant increase in survival. Elsevier 2014-10-31 /pmc/articles/PMC4275809/ /pubmed/25460472 http://dx.doi.org/10.1016/j.ijscr.2014.10.061 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Article
Mateo Vallejo, F.
Dominguez Reinado, M.R.
Medina Achirica, C.
Diaz Oteros, M.
Esteban Ramos, J.L.
Melero Brenes, S.
Giant retroperitoneal leiomyosarcoma. Multiorgan block removal
title Giant retroperitoneal leiomyosarcoma. Multiorgan block removal
title_full Giant retroperitoneal leiomyosarcoma. Multiorgan block removal
title_fullStr Giant retroperitoneal leiomyosarcoma. Multiorgan block removal
title_full_unstemmed Giant retroperitoneal leiomyosarcoma. Multiorgan block removal
title_short Giant retroperitoneal leiomyosarcoma. Multiorgan block removal
title_sort giant retroperitoneal leiomyosarcoma. multiorgan block removal
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275809/
https://www.ncbi.nlm.nih.gov/pubmed/25460472
http://dx.doi.org/10.1016/j.ijscr.2014.10.061
work_keys_str_mv AT mateovallejof giantretroperitonealleiomyosarcomamultiorganblockremoval
AT dominguezreinadomr giantretroperitonealleiomyosarcomamultiorganblockremoval
AT medinaachiricac giantretroperitonealleiomyosarcomamultiorganblockremoval
AT diazoterosm giantretroperitonealleiomyosarcomamultiorganblockremoval
AT estebanramosjl giantretroperitonealleiomyosarcomamultiorganblockremoval
AT melerobreness giantretroperitonealleiomyosarcomamultiorganblockremoval