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Aerosol steroids for the treatment of peristomal mucocutaneous breakdown due to severe eczema

INTRODUCTION: We describe a novel treatment of mucocutaneous peristomal junction breakdown in a patient with severe eczema using aerosol steroids, where conventional methods failed to achieve healing. PRESENTATION OF CASE: Observation and photographic evidence showing resolution of severe peristomal...

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Detalles Bibliográficos
Autores principales: Nicholson, J., Sriskandarajah, S., Moore, J., Clouston, H., Telford, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276280/
https://www.ncbi.nlm.nih.gov/pubmed/25437668
http://dx.doi.org/10.1016/j.ijscr.2014.11.015
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author Nicholson, J.
Sriskandarajah, S.
Moore, J.
Clouston, H.
Telford, K.
author_facet Nicholson, J.
Sriskandarajah, S.
Moore, J.
Clouston, H.
Telford, K.
author_sort Nicholson, J.
collection PubMed
description INTRODUCTION: We describe a novel treatment of mucocutaneous peristomal junction breakdown in a patient with severe eczema using aerosol steroids, where conventional methods failed to achieve healing. PRESENTATION OF CASE: Observation and photographic evidence showing resolution of severe peristomal eczema in a patient, in whom systemic steroids were contraindicated, using a topical aerosol steroid. We found complete resolution of peristomal eczema and symptoms within four weeks. DISCUSSION: Topical aerosol steroids are better tolerated than alcohol based steroid preparations, achieve improved stoma appliance adherence in comparison to oil based steroid preparations and reduce systemic side effects in comparison to systemic oral steroids. CONCLUSION: Aerosol steroids appear to be a safe and effective way to treat refractory peristomal eczema and may be of use in other peristomal inflammatory conditions including contact dermatitis.
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spelling pubmed-42762802014-12-28 Aerosol steroids for the treatment of peristomal mucocutaneous breakdown due to severe eczema Nicholson, J. Sriskandarajah, S. Moore, J. Clouston, H. Telford, K. Int J Surg Case Rep Article INTRODUCTION: We describe a novel treatment of mucocutaneous peristomal junction breakdown in a patient with severe eczema using aerosol steroids, where conventional methods failed to achieve healing. PRESENTATION OF CASE: Observation and photographic evidence showing resolution of severe peristomal eczema in a patient, in whom systemic steroids were contraindicated, using a topical aerosol steroid. We found complete resolution of peristomal eczema and symptoms within four weeks. DISCUSSION: Topical aerosol steroids are better tolerated than alcohol based steroid preparations, achieve improved stoma appliance adherence in comparison to oil based steroid preparations and reduce systemic side effects in comparison to systemic oral steroids. CONCLUSION: Aerosol steroids appear to be a safe and effective way to treat refractory peristomal eczema and may be of use in other peristomal inflammatory conditions including contact dermatitis. Elsevier 2014-11-18 /pmc/articles/PMC4276280/ /pubmed/25437668 http://dx.doi.org/10.1016/j.ijscr.2014.11.015 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Article
Nicholson, J.
Sriskandarajah, S.
Moore, J.
Clouston, H.
Telford, K.
Aerosol steroids for the treatment of peristomal mucocutaneous breakdown due to severe eczema
title Aerosol steroids for the treatment of peristomal mucocutaneous breakdown due to severe eczema
title_full Aerosol steroids for the treatment of peristomal mucocutaneous breakdown due to severe eczema
title_fullStr Aerosol steroids for the treatment of peristomal mucocutaneous breakdown due to severe eczema
title_full_unstemmed Aerosol steroids for the treatment of peristomal mucocutaneous breakdown due to severe eczema
title_short Aerosol steroids for the treatment of peristomal mucocutaneous breakdown due to severe eczema
title_sort aerosol steroids for the treatment of peristomal mucocutaneous breakdown due to severe eczema
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276280/
https://www.ncbi.nlm.nih.gov/pubmed/25437668
http://dx.doi.org/10.1016/j.ijscr.2014.11.015
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