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Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age Group

Glioneuronal neoplasms are rare tumors. Recently, an unusual glioneuronal tumor histologically showing neuropil-like islands has been described. Here, we present such a tumor originating from spinal cord of a 14-year-old girl, who has scoliosis and urinary incontinence. Microscopically, the glial co...

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Detalles Bibliográficos
Autores principales: Comunoglu, Nil, Kilickesmez, Ozgur, Oz, Buge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276692/
https://www.ncbi.nlm.nih.gov/pubmed/25574415
http://dx.doi.org/10.1155/2014/471645
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author Comunoglu, Nil
Kilickesmez, Ozgur
Oz, Buge
author_facet Comunoglu, Nil
Kilickesmez, Ozgur
Oz, Buge
author_sort Comunoglu, Nil
collection PubMed
description Glioneuronal neoplasms are rare tumors. Recently, an unusual glioneuronal tumor histologically showing neuropil-like islands has been described. Here, we present such a tumor originating from spinal cord of a 14-year-old girl, who has scoliosis and urinary incontinence. Microscopically, the glial component was chiefly fibrillary astrocytic, punctuated by neuropil-like islands. Immunohistochemically, glial tissue was GFAP positive, and neuropil-like areas and big neurons were synaptophysin reactive. For astrocytic component Ki-67 proliferation index was 1% and p53 was immunonegative. This case is unique in that in the literature it is the second reported case in pediatric age group that is located at spinal cord.
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spelling pubmed-42766922015-01-08 Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age Group Comunoglu, Nil Kilickesmez, Ozgur Oz, Buge Case Rep Pathol Case Report Glioneuronal neoplasms are rare tumors. Recently, an unusual glioneuronal tumor histologically showing neuropil-like islands has been described. Here, we present such a tumor originating from spinal cord of a 14-year-old girl, who has scoliosis and urinary incontinence. Microscopically, the glial component was chiefly fibrillary astrocytic, punctuated by neuropil-like islands. Immunohistochemically, glial tissue was GFAP positive, and neuropil-like areas and big neurons were synaptophysin reactive. For astrocytic component Ki-67 proliferation index was 1% and p53 was immunonegative. This case is unique in that in the literature it is the second reported case in pediatric age group that is located at spinal cord. Hindawi Publishing Corporation 2014 2014-12-10 /pmc/articles/PMC4276692/ /pubmed/25574415 http://dx.doi.org/10.1155/2014/471645 Text en Copyright © 2014 Nil Comunoglu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Comunoglu, Nil
Kilickesmez, Ozgur
Oz, Buge
Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age Group
title Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age Group
title_full Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age Group
title_fullStr Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age Group
title_full_unstemmed Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age Group
title_short Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age Group
title_sort spinal cord glioneuronal tumor with rosetted neuropil-like islands in pediatric age group
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276692/
https://www.ncbi.nlm.nih.gov/pubmed/25574415
http://dx.doi.org/10.1155/2014/471645
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