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Protective Effect of Quercetin on Melphalan-Induced Oxidative Stress and Impaired Renal and Hepatic Functions in Rat

One major challenge with the use of anticancer agents is the phenomenon of drug-induced toxicity. Melphalan (MPLN) is an alkylating anticancer agent, while quercetin (QCT) is an antioxidant. We investigated the protective role of quercetin against MPLN-induced toxicity. Twenty-five male Wistar rats...

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Detalles Bibliográficos
Autores principales: Olayinka, Ebenezer Tunde, Ore, Ayokanmi, Ola, Olaniyi Solomon, Adeyemo, Oluwatobi Adewumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276702/
https://www.ncbi.nlm.nih.gov/pubmed/25574394
http://dx.doi.org/10.1155/2014/936526