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The Effect of Bortezomib on Expression of Inflammatory Cytokines and Survival in a Murine Sepsis Model Induced by Cecal Ligation and Puncture

PURPOSE: Although the proteasome inhibitor known as bortezomib can modulate the inflammatory process through the nuclear factor-kappa B signaling pathway, the immunomodulatory effect of pre-incubated bortezomib has not been fully evaluated for inflammation by infectious agents. Therefore, we evaluat...

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Detalles Bibliográficos
Autores principales: Han, Sang Hoon, Kim, Jin Seok, Woo, Jun Hee, Jeong, Su Jin, Shin, Jeon-Soo, Ahn, Young Soo, Kim, June Myung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276744/
https://www.ncbi.nlm.nih.gov/pubmed/25510754
http://dx.doi.org/10.3349/ymj.2015.56.1.112