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Sumoylation is Required for the Cytoplasmic Accumulation of a Subset of mRNAs

In order to discover novel proteins that promote the nuclear export of newly synthesized mRNAs in mammalian cells, we carried out a limited RNAi screen for proteins required for the proper cytoplasmic distribution of a model intronless mRNA. From this screen we obtained two hits, Ubc9 (SUMO-conjugat...

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Detalles Bibliográficos
Autores principales:	Zhang, Hui, Mahadevan, Kohila, Palazzo, Alexander F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276922/ https://www.ncbi.nlm.nih.gov/pubmed/25333844 http://dx.doi.org/10.3390/genes5040982

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