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Mechanisms of Hepatocyte Growth Factor Activation in Cancer Tissues

Hepatocyte growth factor/scatter factor (HGF/SF) plays critical roles in cancer progression through its specific receptor, MET. HGF/SF is usually synthesized and secreted as an inactive proform (pro-HGF/SF) by stromal cells, such as fibroblasts. Several serine proteases are reported to convert pro-H...

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Detalles Bibliográficos
Autores principales:	Kawaguchi, Makiko, Kataoka, Hiroaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276949/ https://www.ncbi.nlm.nih.gov/pubmed/25268161 http://dx.doi.org/10.3390/cancers6041890

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