Cargando…
Auranofin, an Anti-Rheumatic Gold Compound, Modulates Apoptosis by Elevating the Intracellular Calcium Concentration ([Ca(2+)](i)) in MCF-7 Breast Cancer Cells
Auranofin, a transition metal complex is used for the treatment of rheumatoid arthritis but is also an effective anti-cancer drug. We investigate the effects of Auranofin in inducing cell death by apoptosis and whether these changes are correlated to changes of intracellular calcium concentration ([...
Autores principales: | Varghese, Elizabeth, Büsselberg, Dietrich |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276964/ https://www.ncbi.nlm.nih.gov/pubmed/25383481 http://dx.doi.org/10.3390/cancers6042243 |
Ejemplares similares
-
Repurposing Auranofin, an Anti-Rheumatic Gold Compound, to Treat Acne Vulgaris by Targeting the NLRP3 Inflammasome
por: Yang, Gabsik, et al.
Publicado: (2020) -
Auranofin, an Anti-rheumatic Gold Drug, Aggravates the Radiation-Induced Acute Intestinal Injury in Mice
por: Lee, Eun Sang, et al.
Publicado: (2019) -
Targeting Intracellular Calcium Signaling ([Ca(2+)](i)) to Overcome Acquired Multidrug Resistance of Cancer Cells: A Mini-Overview
por: Büsselberg, Dietrich, et al.
Publicado: (2017) -
The Role of Intracellular Calcium for the Development and Treatment of Neuroblastoma
por: Satheesh, Noothan Jyothi, et al.
Publicado: (2015) -
Enhancement of Auranofin-Induced Apoptosis in MCF-7 Human Breast Cells by Selenocystine, a Synergistic Inhibitor of Thioredoxin Reductase
por: Liu, Chaoran, et al.
Publicado: (2013)