A thorough QT study in the context of an uptitration regimen with selexipag, a selective oral prostacyclin receptor agonist

The effects of selexipag and its active metabolite ACT-333679 on cardiac repolarization were assessed in a thorough QT study as per International Conference on Harmonisation E14 guidance. In this randomized, double-blind, placebo/positive-controlled, parallel-group study, healthy male and female sub...

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Detalles Bibliográficos
Autores principales: Hoch, Matthias, Darpo, Borje, Remenova, Tatiana, Stoltz, Randall, Zhou, Meijian, Kaufmann, Priska, Bruderer, Shirin, Dingemanse, Jasper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277127/
https://www.ncbi.nlm.nih.gov/pubmed/25552906
http://dx.doi.org/10.2147/DDDT.S75565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277127/
https://www.ncbi.nlm.nih.gov/pubmed/25552906
http://dx.doi.org/10.2147/DDDT.S75565

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