Cargando…

Imaging of CAIX-expressing xenografts in vivo using (99m)Tc-HEHEHE-ZCAIX:1 Affibody molecule

Carbonic anhydrase IX (CAIX) is a transmembrane enzyme involved in regulation of tissue pH balance. In cancer, CAIX expression is associated with tumor hypoxia. CAIX is also overexpressed in renal cell carcinoma and is a molecular target for the therapeutic antibody cG250 (girentuximab). Radionuclid...

Descripción completa

Detalles Bibliográficos
Autores principales:	HONARVAR, HADIS, GAROUSI, JAVAD, GUNNERIUSSON, ELIN, HÖIDÉN-GUTHENBERG, INGMARIE, ALTAI, MOHAMED, WIDSTRÖM, CHARLES, TOLMACHEV, VLADIMIR, FREJD, FREDRIK Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277246/ https://www.ncbi.nlm.nih.gov/pubmed/25434612 http://dx.doi.org/10.3892/ijo.2014.2782

Ejemplares similares

In vivo depletion of serum IgG by an affibody molecule binding the neonatal Fc receptor
por: Seijsing, Johan, et al.
Publicado: (2018)

Cellular Effects of HER3-Specific Affibody Molecules
por: Göstring, Lovisa, et al.
Publicado: (2012)

Comparative evaluation of affibody- and antibody fragments-based CAIX imaging probes in mice bearing renal cell carcinoma xenografts
por: Garousi, Javad, et al.
Publicado: (2019)

Affibody-Mediated Sequestration of Amyloid β Demonstrates Preventive Efficacy in a Transgenic Alzheimer’s Disease Mouse Model
por: Boutajangout, Allal, et al.
Publicado: (2019)

Evaluation of (99m)Tc-Z(IGF1R:4551)-GGGC affibody molecule, a new probe for imaging of insulin-like growth factor type 1 receptor expression
por: Mitran, Bogdan, et al.
Publicado: (2014)

Izokibep: Preclinical development and first-in-human study of a novel IL-17A neutralizing Affibody molecule in patients with plaque psoriasis
por: Klint, Susanne, et al.
Publicado: (2023)

Influence of composition of cysteine-containing peptide-based chelators on biodistribution of (99m)Tc-labeled anti-EGFR affibody molecules
por: Oroujeni, Maryam, et al.
Publicado: (2018)

Inhibiting HER3-Mediated Tumor Cell Growth with Affibody Molecules Engineered to Low Picomolar Affinity by Position-Directed Error-Prone PCR-Like Diversification
por: Malm, Magdalena, et al.
Publicado: (2013)

Correction: Inhibiting HER3-Mediated Tumor Cell Growth with Affibody Molecules Engineered to Low Picomolar Affinity by Position-Directed Error-Prone PCR-Like Diversification
por: Malm, Magdalena, et al.
Publicado: (2013)

Feasibility of Affibody Molecule-Based PNA-Mediated Radionuclide Pretargeting of Malignant Tumors
por: Honarvar, Hadis, et al.
Publicado: (2016)

Site-Specific Radioiodination of HER2-Targeting Affibody Molecules using 4-Iodophenethylmaleimide Decreases Renal Uptake of Radioactivity
por: Strand, Joanna, et al.
Publicado: (2015)

Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of (68)Ga-Labeled Tracers
por: Dahlsson Leitao, Charles, et al.
Publicado: (2019)

Phase I clinical evaluation of (99m)Tc-labeled Affibody molecule for imaging HER2 expression in breast cancer
por: Bragina, Olga, et al.
Publicado: (2023)

Influence of Several Compounds and Drugs on the Renal Uptake of Radiolabeled Affibody Molecules
por: Garousi, Javad, et al.
Publicado: (2020)

CAIX-targeting radiotracers for hypoxia imaging in head and neck cancer models
por: Huizing, Fokko J., et al.
Publicado: (2019)

Feasibility of imaging of epidermal growth factor receptor expression with ZEGFR:2377 affibody molecule labeled with (99m)Tc using a peptide-based cysteine-containing chelator
por: Andersson, Ken G., et al.
Publicado: (2016)

Preclinical Evaluation of (99m)Tc-ZHER2:41071, a Second-Generation Affibody-Based HER2-Visualizing Imaging Probe with a Low Renal Uptake
por: Oroujeni, Maryam, et al.
Publicado: (2021)

An affibody-adalimumab hybrid blocks combined IL-6 and TNF-triggered serum amyloid A secretion in vivo
por: Yu, Feifan, et al.
Publicado: (2014)

Radionuclide Therapy of HER2-Expressing Xenografts Using [(177)Lu]Lu-ABY-027 Affibody Molecule Alone and in Combination with Trastuzumab
por: Liu, Yongsheng, et al.
Publicado: (2023)

Influence of Macrocyclic Chelators on the Targeting Properties of (68)Ga-Labeled Synthetic Affibody Molecules: Comparison with (111)In-Labeled Counterparts
por: Strand, Joanna, et al.
Publicado: (2013)

Simultaneous targeting of two ligand-binding sites on VEGFR2 using biparatopic Affibody molecules results in dramatically improved affinity
por: Fleetwood, Filippa, et al.
Publicado: (2014)

Evaluating the Therapeutic Efficacy of Mono- and Bivalent Affibody-Based Fusion Proteins Targeting HER3 in a Pancreatic Cancer Xenograft Model
por: Dahlsson Leitao, Charles, et al.
Publicado: (2020)

Experimental Therapy of HER2-Expressing Xenografts Using the Second-Generation HER2-Targeting Affibody Molecule (188)Re-ZHER2:41071
por: Liu, Yongsheng, et al.
Publicado: (2022)

Affibody molecules as engineered protein drugs
por: Frejd, Fredrik Y, et al.
Publicado: (2017)

Novel small (99m)Tc-labeled affibody molecular probe for PD-L1 receptor imaging
por: Liang, Zhigang, et al.
Publicado: (2022)

Incorporation of a Hydrophilic Spacer Reduces Hepatic Uptake of HER2-Targeting Affibody–DM1 Drug Conjugates
por: Ding, Haozhong, et al.
Publicado: (2019)

Molecular design of radiocopper-labelled Affibody molecules
por: Tolmachev, Vladimir, et al.
Publicado: (2018)

Development of an optimal imaging strategy for selection of patients for affibody-based PNA-mediated radionuclide therapy
por: Vorobyeva, Anzhelika, et al.
Publicado: (2018)

Improved contrast of affibody-mediated imaging of HER3 expression in mouse xenograft model through co-injection of a trivalent affibody for in vivo blocking of hepatic uptake
por: Rosestedt, Maria, et al.
Publicado: (2019)

Affibody Molecules as Targeting Vectors for PET Imaging
por: Tolmachev, Vladimir, et al.
Publicado: (2020)

In vivo evaluation of a novel format of a bivalent HER3-targeting and albumin-binding therapeutic affibody construct
por: Bass, Tarek Z., et al.
Publicado: (2017)

Kinetic analysis of HER2-binding ABY-025 Affibody molecule using dynamic PET in patients with metastatic breast cancer
por: Alhuseinalkhudhur, Ali, et al.
Publicado: (2020)

Imaging using radiolabelled targeted proteins: radioimmunodetection and beyond
por: Garousi, Javad, et al.
Publicado: (2020)

Evaluation of an Affibody-Based Binder for Imaging of Immune Check-Point Molecule B7-H3
por: Oroujeni, Maryam, et al.
Publicado: (2022)

Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs
por: Altai, Mohamed, et al.
Publicado: (2018)

Optimal composition and position of histidine-containing tags improves biodistribution of (99m)Tc-labeled DARPin G3
por: Vorobyeva, Anzhelika, et al.
Publicado: (2019)

PET imaging of epidermal growth factor receptor expression in tumours using (89)Zr-labelled ZEGFR:2377 affibody molecules
por: GAROUSI, JAVAD, et al.
Publicado: (2016)

Preclinical Evaluation of [(68)Ga]Ga-DFO-ZEGFR:2377: A Promising Affibody-Based Probe for Noninvasive PET Imaging of EGFR Expression in Tumors
por: Oroujeni, Maryam, et al.
Publicado: (2018)

The use of radiocobalt as a label improves imaging of EGFR using DOTA-conjugated Affibody molecule
por: Garousi, Javad, et al.
Publicado: (2017)

Radiosynthesis, optimization and pharmacokinetic study of the (99m)Tc-labeled human epidermal growth factor receptor 2 affibody molecule probe (99m)Tc-(HE)(3)Z(HER2:V2)
por: Hu, Xianwen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ic3i9acjn94iectoh5vt94pq2c