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JARID2 Is Involved in Transforming Growth Factor-Beta-Induced Epithelial-Mesenchymal Transition of Lung and Colon Cancer Cell Lines

Histone methylation plays a crucial role in various biological and pathological processes including cancer development. In this study, we discovered that JARID2, an interacting component of Polycomb repressive complex-2 (PRC2) that catalyzes methylation of lysine 27 of histone H3 (H3K27), was involv...

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Detalles Bibliográficos
Autores principales: Tange, Shoichiro, Oktyabri, Dulamsuren, Terashima, Minoru, Ishimura, Akihiko, Suzuki, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277293/
https://www.ncbi.nlm.nih.gov/pubmed/25542019
http://dx.doi.org/10.1371/journal.pone.0115684