The Roles of Co-Chaperone CCRP/DNAJC7 in Cyp2b10 Gene Activation and Steatosis Development in Mouse Livers

Cytoplasmic constitutive active/androstane receptor (CAR) retention protein (CCRP and also known as DNAJC7) is a co-chaperone previously characterized to retain nuclear receptor CAR in the cytoplasm of HepG2 cells. Here we have produced CCRP knockout (KO) mice and demonstrated that CCRP regulates CA...

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Detalles Bibliográficos
Autores principales: Ohno, Marumi, Kanayama, Tomohiko, Moore, Rick, Ray, Manas, Negishi, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277317/
https://www.ncbi.nlm.nih.gov/pubmed/25542016
http://dx.doi.org/10.1371/journal.pone.0115663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277317/
https://www.ncbi.nlm.nih.gov/pubmed/25542016
http://dx.doi.org/10.1371/journal.pone.0115663

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