Immunosuppression after Sepsis: Systemic Inflammation and Sepsis Induce a Loss of Naïve T-Cells but No Enduring Cell-Autonomous Defects in T-Cell Function

Sepsis describes the life-threatening systemic inflammatory response (SIRS) of an organism to an infection and is the leading cause of mortality on intensive care units (ICU) worldwide. An acute episode of sepsis is characterized by the extensive release of cytokines and other mediators resulting in...

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Detalles Bibliográficos
Autores principales: Markwart, Robby, Condotta, Stephanie A., Requardt, Robert P., Borken, Farina, Schubert, Katja, Weigel, Cynthia, Bauer, Michael, Griffith, Thomas S., Förster, Martin, Brunkhorst, Frank M., Badovinac, Vladimir P., Rubio, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277344/
https://www.ncbi.nlm.nih.gov/pubmed/25541945
http://dx.doi.org/10.1371/journal.pone.0115094

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