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Increasing Fatty Acid Oxidation Remodels the Hypothalamic Neurometabolome to Mitigate Stress and Inflammation
Modification of hypothalamic fatty acid (FA) metabolism can improve energy homeostasis and prevent hyperphagia and excessive weight gain in diet-induced obesity (DIO) from a diet high in saturated fatty acids. We have shown previously that C75, a stimulator of carnitine palmitoyl transferase-1 (CPT-...
Autores principales: | McFadden, Joseph W., Aja, Susan, Li, Qun, Bandaru, Veera V. R., Kim, Eun-Kyoung, Haughey, Norman J., Kuhajda, Francis P., Ronnett, Gabriele V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277346/ https://www.ncbi.nlm.nih.gov/pubmed/25541737 http://dx.doi.org/10.1371/journal.pone.0115642 |
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