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Increasing Fatty Acid Oxidation Remodels the Hypothalamic Neurometabolome to Mitigate Stress and Inflammation

Modification of hypothalamic fatty acid (FA) metabolism can improve energy homeostasis and prevent hyperphagia and excessive weight gain in diet-induced obesity (DIO) from a diet high in saturated fatty acids. We have shown previously that C75, a stimulator of carnitine palmitoyl transferase-1 (CPT-...

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Detalles Bibliográficos
Autores principales: McFadden, Joseph W., Aja, Susan, Li, Qun, Bandaru, Veera V. R., Kim, Eun-Kyoung, Haughey, Norman J., Kuhajda, Francis P., Ronnett, Gabriele V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277346/
https://www.ncbi.nlm.nih.gov/pubmed/25541737
http://dx.doi.org/10.1371/journal.pone.0115642

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