Defects in Mitochondrial ATP Synthesis in Dystrophin-Deficient Mdx Skeletal Muscles May Be Caused by Complex I Insufficiency

Duchenne Muscular Dystrophy is a chronic, progressive and ultimately fatal skeletal muscle wasting disease characterised by sarcolemmal fragility and intracellular Ca(2+) dysregulation secondary to the absence of dystrophin. Mounting literature also suggests that the dysfunction of key energy system...

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Detalles Bibliográficos
Autores principales: Rybalka, Emma, Timpani, Cara A., Cooke, Matthew B., Williams, Andrew D., Hayes, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277356/
https://www.ncbi.nlm.nih.gov/pubmed/25541951
http://dx.doi.org/10.1371/journal.pone.0115763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277356/
https://www.ncbi.nlm.nih.gov/pubmed/25541951
http://dx.doi.org/10.1371/journal.pone.0115763

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