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Outcomes of Bronchial Artery Embolization for Life-Threatening Hemoptysis Secondary to Tuberculosis

OBJECTIVE: To appraise the immediate and long-term outcomes of bronchial arterial embolization for life-threatening hemoptysis secondary to tuberculosis. METHODS: 112 patients with life-threatening hemoptysis due to tuberculosis underwent bronchial artery embolization from January 2004 to February 2...

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Autores principales: Pei, Renguang, Zhou, Yunfeng, Wang, Guoxiang, Wang, Heping, Huang, Xinyu, Yan, Xiaoxing, Yang, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277402/
https://www.ncbi.nlm.nih.gov/pubmed/25541693
http://dx.doi.org/10.1371/journal.pone.0115956
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author Pei, Renguang
Zhou, Yunfeng
Wang, Guoxiang
Wang, Heping
Huang, Xinyu
Yan, Xiaoxing
Yang, Xiaohua
author_facet Pei, Renguang
Zhou, Yunfeng
Wang, Guoxiang
Wang, Heping
Huang, Xinyu
Yan, Xiaoxing
Yang, Xiaohua
author_sort Pei, Renguang
collection PubMed
description OBJECTIVE: To appraise the immediate and long-term outcomes of bronchial arterial embolization for life-threatening hemoptysis secondary to tuberculosis. METHODS: 112 patients with life-threatening hemoptysis due to tuberculosis underwent bronchial artery embolization from January 2004 to February 2014. Life-threatening hemoptysis was defined as expectoration of at least 400 ml of blood in 24 hour. The median follow-up is 20 months, ranging from 2 to 52 months. RESULTS: The hemoptysis control rate was 86.6% at 14 days, 84.8% at 30 days, 78.6% at 240 days, 75.9% at 360 days, respectively. None of these characteristics, including gender, age and tuberculosis status, was significantly associated with immediate control of bleeding. Patients with active tuberculosis had a significantly longer recurrence-free duration than did patients with inactive tuberculosis (P = 0.040), which was further confirmed by Cox regression hazards model (P = 0.046). There was no spinal cord complication or mortality related to bronchial artery embolization. The most common complication was transient chest pain. CONCLUSION: Bronchial arterial embolization is an effective and safe technique in the management of life-threatening hemoptysis secondary to tuberculosis. Active tuberculosis may be associated with a lower rate of recurrence of hemoptysis.
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spelling pubmed-42774022014-12-31 Outcomes of Bronchial Artery Embolization for Life-Threatening Hemoptysis Secondary to Tuberculosis Pei, Renguang Zhou, Yunfeng Wang, Guoxiang Wang, Heping Huang, Xinyu Yan, Xiaoxing Yang, Xiaohua PLoS One Research Article OBJECTIVE: To appraise the immediate and long-term outcomes of bronchial arterial embolization for life-threatening hemoptysis secondary to tuberculosis. METHODS: 112 patients with life-threatening hemoptysis due to tuberculosis underwent bronchial artery embolization from January 2004 to February 2014. Life-threatening hemoptysis was defined as expectoration of at least 400 ml of blood in 24 hour. The median follow-up is 20 months, ranging from 2 to 52 months. RESULTS: The hemoptysis control rate was 86.6% at 14 days, 84.8% at 30 days, 78.6% at 240 days, 75.9% at 360 days, respectively. None of these characteristics, including gender, age and tuberculosis status, was significantly associated with immediate control of bleeding. Patients with active tuberculosis had a significantly longer recurrence-free duration than did patients with inactive tuberculosis (P = 0.040), which was further confirmed by Cox regression hazards model (P = 0.046). There was no spinal cord complication or mortality related to bronchial artery embolization. The most common complication was transient chest pain. CONCLUSION: Bronchial arterial embolization is an effective and safe technique in the management of life-threatening hemoptysis secondary to tuberculosis. Active tuberculosis may be associated with a lower rate of recurrence of hemoptysis. Public Library of Science 2014-12-26 /pmc/articles/PMC4277402/ /pubmed/25541693 http://dx.doi.org/10.1371/journal.pone.0115956 Text en © 2014 Pei et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Pei, Renguang
Zhou, Yunfeng
Wang, Guoxiang
Wang, Heping
Huang, Xinyu
Yan, Xiaoxing
Yang, Xiaohua
Outcomes of Bronchial Artery Embolization for Life-Threatening Hemoptysis Secondary to Tuberculosis
title Outcomes of Bronchial Artery Embolization for Life-Threatening Hemoptysis Secondary to Tuberculosis
title_full Outcomes of Bronchial Artery Embolization for Life-Threatening Hemoptysis Secondary to Tuberculosis
title_fullStr Outcomes of Bronchial Artery Embolization for Life-Threatening Hemoptysis Secondary to Tuberculosis
title_full_unstemmed Outcomes of Bronchial Artery Embolization for Life-Threatening Hemoptysis Secondary to Tuberculosis
title_short Outcomes of Bronchial Artery Embolization for Life-Threatening Hemoptysis Secondary to Tuberculosis
title_sort outcomes of bronchial artery embolization for life-threatening hemoptysis secondary to tuberculosis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277402/
https://www.ncbi.nlm.nih.gov/pubmed/25541693
http://dx.doi.org/10.1371/journal.pone.0115956
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