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IDO1 and IDO2 Non-Synonymous Gene Variants: Correlation with Crohn's Disease Risk and Clinical Phenotype

BACKGROUND: Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract. Genetic polymorphisms can confer CD risk and influence disease phenotype. Indoleamine 2,3 dioxygenase-1 (IDO1) is one of the most over-expressed genes in CD and mediates potent anti-inflammatory ef...

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Detalles Bibliográficos
Autores principales:	Lee, Alexander, Kanuri, Navya, Zhang, Yuanhao, Sayuk, Gregory S., Li, Ellen, Ciorba, Matthew A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277413/ https://www.ncbi.nlm.nih.gov/pubmed/25541686 http://dx.doi.org/10.1371/journal.pone.0115848

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