Expression of Ror2 Mediates Invasive Phenotypes in Renal Cell Carcinoma

Ror2 is a Wnt ligand receptor that is overexpressed in a variety of tumors including clear cell renal cell carcinoma (ccRCC). Here we demonstrate that expression of wild type Ror2 results in increased tumorigenic properties in in vitro cell culture and in vivo xenograft models. In addition, Ror2 exp...

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Detalles Bibliográficos
Autores principales: Rasmussen, Neal R., Debebe, Zufan, Wright, Tricia M., Brooks, Samira A., Sendor, Adam B., Brannon, A . Rose, Hakimi, A . Ari, Hsieh, James J., Choueiri, Toni K., Tamboli, Pheroze, Maranchie, Jodi K., Hinds, Peter, Wallen, Eric M., Simpson, Catherine, Norris, Jacqueline L., Janzen, William P., Rathmell, W. Kimryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277431/
https://www.ncbi.nlm.nih.gov/pubmed/25542006
http://dx.doi.org/10.1371/journal.pone.0116101

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