Phosphoinositide-3 Kinase Inhibition Modulates Responses to Rhinovirus by Mechanisms that Are Predominantly Independent of Autophagy

Human rhinoviruses (HRV) are a major cause of exacerbations of airways disease. Aspects of cell signalling responses to HRV infection remain unclear, particularly with regard to signalling via PI3K, and the PI3K-dependent pathway, autophagy. We investigated the roles of PI3K and autophagy in the res...

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Detalles Bibliográficos
Autores principales: Ismail, Saila, Stokes, Clare A., Prestwich, Elizabeth C., Roberts, Rebecca L., Juss, Jatinder K., Sabroe, Ian, Parker, Lisa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277460/
https://www.ncbi.nlm.nih.gov/pubmed/25541728
http://dx.doi.org/10.1371/journal.pone.0116055

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