Cargando…

The IL-13/IL-4Rα axis is involved in tuberculosis-associated pathology

Human tuberculosis (TB) is a leading global health threat and still constitutes a major medical challenge. However, mechanisms governing tissue pathology during post-primary TB remain elusive, partly because genetically or immunologically tractable animal models are lacking. In human TB, the demonst...

Descripción completa

Detalles Bibliográficos
Autores principales:	Heitmann, Lisa, Abad Dar, Mahin, Schreiber, Tanja, Erdmann, Hanna, Behrends, Jochen, Mckenzie, Andrew NJ, Brombacher, Frank, Ehlers, Stefan, Hölscher, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2014
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277691/ https://www.ncbi.nlm.nih.gov/pubmed/24979482 http://dx.doi.org/10.1002/path.4399

Ejemplares similares

Arginase-1 Is Responsible for IL-13-Mediated Susceptibility to Trypanosoma cruzi Infection
por: Abad Dar, Mahin, et al.
Publicado: (2018)

During acute experimental infection with the reticulotropic Trypanosoma cruzi strain Tulahuen IL-22 is induced IL-23-dependently but is dispensable for protection
por: Erdmann, Hanna, et al.
Publicado: (2016)

Suppressor of Cytokine Signaling 3 in Macrophages Prevents Exacerbated Interleukin-6-Dependent Arginase-1 Activity and Early Permissiveness to Experimental Tuberculosis
por: Schmok, Erik, et al.
Publicado: (2017)

IL-22 Is Mainly Produced by IFNγ-Secreting Cells but Is Dispensable for Host Protection against Mycobacterium tuberculosis Infection
por: Behrends, Jochen, et al.
Publicado: (2013)

High-Dose Mycobacterium tuberculosis H37rv Infection in IL-17A- and IL-17A/F-Deficient Mice
por: Ritter, Kristina, et al.
Publicado: (2022)

IL-6 Is Not Absolutely Essential for the Development of a TH17 Immune Response after an Aerosol Infection with Mycobacterium tuberculosis H37rv
por: Ritter, Kristina, et al.
Publicado: (2020)

A Mutation in IL4RA Is Associated with the Degree of Pathology in Human TB Patients
por: Hölscher, Christoph, et al.
Publicado: (2016)

Myeloid-IL4Rα is an indispensable link in IL-33-ILCs-IL-13-IL4Rα axis of eosinophil recruitment in murine lungs
por: Patial, Sonika, et al.
Publicado: (2021)

Blocking IL-10 receptor signaling ameliorates Mycobacterium tuberculosis infection during influenza-induced exacerbation
por: Ring, Sarah, et al.
Publicado: (2019)

Identification of an interleukin (IL)-25–dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion
por: Fallon, Padraic G., et al.
Publicado: (2006)

Simultaneous Disruption of Interleukin (IL)-4 and IL-13 Defines Individual Roles in T Helper Cell Type 2–mediated Responses
por: McKenzie, Grahame J., et al.
Publicado: (1999)

The IL-4/IL-13 signaling axis promotes prostatic fibrosis
por: D’Arcy, Quentin, et al.
Publicado: (2022)

Interleukin (IL)-4–independent Induction of Immunoglobulin (Ig)E, and Perturbation of T Cell Development in Transgenic Mice Expressing IL-13
por: Emson, Claire L., et al.
Publicado: (1998)

Interleukin-23 instructs protective multifunctional CD4 T cell responses after immunization with the Mycobacterium tuberculosis subunit vaccine H1 DDA/TDB independently of interleukin-17A
por: Ritter, Kristina, et al.
Publicado: (2021)

IL-4/IL-13 independent goblet cell hyperplasia in experimental helminth infections
por: Marillier, Reece G, et al.
Publicado: (2008)

IL-4/IL-13 axis as therapeutic targets in allergic rhinitis and asthma
por: Nur Husna, Siti Muhamad, et al.
Publicado: (2022)

Endogenous IL-13 Plays a Crucial Role in Liver Granuloma Maturation During Leishmania donovani Infection, Independent of IL-4Rα–Responsive Macrophages and Neutrophils
por: McFarlane, Emma, et al.
Publicado: (2011)

Investigation on Probable Association Between IL-13, IL-13RA1, and IL-13RA2 Genes Polymorphism and Pulmonary Tuberculosis
por: Li, Hong-Miao, et al.
Publicado: (2022)

ILC2 activation by keratinocyte-derived IL-25 drives IL-13 production at sites of allergic skin inflammation
por: Leyva-Castillo, Juan Manuel, et al.
Publicado: (2020)

IL-33/IL-31 Axis in Osteoporosis
por: De Martinis, Massimo, et al.
Publicado: (2020)

IL-33/13 Axis and IL-4/31 Axis Play Distinct Roles in Inflammatory Process and Itch in Psoriasis and Atopic Dermatitis
por: Bodoor, Khaldon, et al.
Publicado: (2020)

IL-4Rα-Dependent Alternative Activation of Macrophages Is Not Decisive for Mycobacterium tuberculosis Pathology and Bacterial Burden in Mice
por: Guler, Reto, et al.
Publicado: (2015)

Tralokinumab Effectively Disrupts the IL-13/IL-13Rα1/IL-4Rα Signaling Complex but Not the IL-13/IL-13Rα2 Complex
por: Tollenaere, Maxim A.X., et al.
Publicado: (2023)

The IL-4/-13 Axis and Its Blocking in the Treatment of Atopic Dermatitis
por: Pappa, Georgia, et al.
Publicado: (2022)

The IL-23/IL-22/IL-18 axis in murine Campylobacter jejuni infection
por: Heimesaat, Markus M., et al.
Publicado: (2016)

IL-4, IL-13 and IFN-γ -induced genes in highly purified human neutrophils
por: Kummola, Laura, et al.
Publicado: (2023)

Differential Targeting of c-Maf, Bach-1, and Elmo-1 by microRNA-143 and microRNA-365 Promotes the Intracellular Growth of Mycobacterium tuberculosis in Alternatively IL-4/IL-13 Activated Macrophages
por: Tamgue, Ousman, et al.
Publicado: (2019)

Intrinsic Defect in T Cell Production of Interleukin (IL)-13 in the Absence of Both IL-5 and Eotaxin Precludes the Development of Eosinophilia and Airways Hyperreactivity in Experimental Asthma
por: Mattes, Joerg, et al.
Publicado: (2002)

Validation of an IFNγ/IL2 FluoroSpot assay for clinical trial monitoring
por: Körber, Nina, et al.
Publicado: (2016)

Commensal-dependent expression of IL-25 regulates the IL-23–IL-17 axis in the intestine
por: Zaph, Colby, et al.
Publicado: (2008)

IFN-γ, IL-4 and IL-13 modulate responsiveness of human airway smooth muscle cells to IL-13
por: Moynihan, Barry J, et al.
Publicado: (2008)

IL-33 Enhanced the Proliferation and Constitutive Production of IL-13 and IL-5 by Fibrocytes
por: Hayashi, Hisako, et al.
Publicado: (2014)

Involvement of IL-4, IL-13 and Their Receptors in Pancreatic Cancer
por: Shi, Jingwei, et al.
Publicado: (2021)

Significance of Interleukin (IL)-4 and IL-13 in Inflammatory Arthritis
por: Iwaszko, Milena, et al.
Publicado: (2021)

The Role of IL-13 and IL-4 in Adipose Tissue Fibrosis
por: Arndt, Lilli, et al.
Publicado: (2023)

IL-33/IL-31 Axis: A Potential Inflammatory Pathway
por: Di Salvo, Eleonora, et al.
Publicado: (2018)

IL-33/IL-31 Axis in Immune-Mediated and Allergic Diseases
por: Murdaca, Giuseppe, et al.
Publicado: (2019)

The IL-33/IL-31 Axis in Allergic and Immune-Mediated Diseases
por: Murdaca, Giuseppe, et al.
Publicado: (2023)

Role of IL-4Rα during acute schistosomiasis in mice
por: Ndlovu, H, et al.
Publicado: (2014)

IL-4/IL-13 Axis in Allergic Rhinitis: Elevated Serum Cytokines Levels and Inverse Association With Tight Junction Molecules Expression
por: Nur Husna, Siti Muhamad, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vdhuhj5hlp8j72198s6hvf8t78