Randomized pharmacokinetic evaluation of different rifabutin doses in African HIV- infected tuberculosis patients on lopinavir/ritonavir-based antiretroviral therapy

BACKGROUND: Pharmacokinetic interactions between rifampicin and protease inhibitors (PIs) complicate the management of HIV-associated tuberculosis. Rifabutin is an alternative rifamycin, for patients requiring PIs. Recently some international guidelines have recommended a higher dose of rifabutin (1...

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Detalles Bibliográficos
Autores principales: Naiker, Suhashni, Connolly, Cathy, Wiesner, Lubbe, Kellerman, Tracey, Reddy, Tarylee, Harries, Anthony, McIlleron, Helen, Lienhardt, Christian, Pym, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277828/
https://www.ncbi.nlm.nih.gov/pubmed/25406657
http://dx.doi.org/10.1186/2050-6511-15-61

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277828/
https://www.ncbi.nlm.nih.gov/pubmed/25406657
http://dx.doi.org/10.1186/2050-6511-15-61

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