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Randomized pharmacokinetic evaluation of different rifabutin doses in African HIV- infected tuberculosis patients on lopinavir/ritonavir-based antiretroviral therapy

BACKGROUND: Pharmacokinetic interactions between rifampicin and protease inhibitors (PIs) complicate the management of HIV-associated tuberculosis. Rifabutin is an alternative rifamycin, for patients requiring PIs. Recently some international guidelines have recommended a higher dose of rifabutin (1...

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Detalles Bibliográficos
Autores principales:	Naiker, Suhashni, Connolly, Cathy, Wiesner, Lubbe, Kellerman, Tracey, Reddy, Tarylee, Harries, Anthony, McIlleron, Helen, Lienhardt, Christian, Pym, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277828/ https://www.ncbi.nlm.nih.gov/pubmed/25406657 http://dx.doi.org/10.1186/2050-6511-15-61

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