Rumphellaoic Acid A, a Novel Sesquiterpenoid from the Formosan Gorgonian Coral Rumphella antipathies

A novel sesquiterpenoid, rumphellaoic acid A (1), was isolated from the gorgonian coral Rumphella antipathies, and was found to possess a carbon skeleton that was obtained for the first time from a natural sources. The structure of 1 was elucidated by spectroscopic methods and this compound and was...

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Autores principales: Chung, Hsu-Ming, Wang, Wei-Hsien, Hwang, Tsong-Long, Fang, Lee-Shing, Wen, Zhi-Hong, Chen, Jih-Jung, Wu, Yang-Chang, Sung, Ping-Jyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278205/
https://www.ncbi.nlm.nih.gov/pubmed/25486110
http://dx.doi.org/10.3390/md12125856
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author Chung, Hsu-Ming
Wang, Wei-Hsien
Hwang, Tsong-Long
Fang, Lee-Shing
Wen, Zhi-Hong
Chen, Jih-Jung
Wu, Yang-Chang
Sung, Ping-Jyun
author_facet Chung, Hsu-Ming
Wang, Wei-Hsien
Hwang, Tsong-Long
Fang, Lee-Shing
Wen, Zhi-Hong
Chen, Jih-Jung
Wu, Yang-Chang
Sung, Ping-Jyun
author_sort Chung, Hsu-Ming
collection PubMed
description A novel sesquiterpenoid, rumphellaoic acid A (1), was isolated from the gorgonian coral Rumphella antipathies, and was found to possess a carbon skeleton that was obtained for the first time from a natural sources. The structure of 1 was elucidated by spectroscopic methods and this compound and was found to exert a moderate inhibitory effect on the release of elastase by human neutrophils.
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spelling pubmed-42782052015-01-08 Rumphellaoic Acid A, a Novel Sesquiterpenoid from the Formosan Gorgonian Coral Rumphella antipathies Chung, Hsu-Ming Wang, Wei-Hsien Hwang, Tsong-Long Fang, Lee-Shing Wen, Zhi-Hong Chen, Jih-Jung Wu, Yang-Chang Sung, Ping-Jyun Mar Drugs Communication A novel sesquiterpenoid, rumphellaoic acid A (1), was isolated from the gorgonian coral Rumphella antipathies, and was found to possess a carbon skeleton that was obtained for the first time from a natural sources. The structure of 1 was elucidated by spectroscopic methods and this compound and was found to exert a moderate inhibitory effect on the release of elastase by human neutrophils. MDPI 2014-12-04 /pmc/articles/PMC4278205/ /pubmed/25486110 http://dx.doi.org/10.3390/md12125856 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Chung, Hsu-Ming
Wang, Wei-Hsien
Hwang, Tsong-Long
Fang, Lee-Shing
Wen, Zhi-Hong
Chen, Jih-Jung
Wu, Yang-Chang
Sung, Ping-Jyun
Rumphellaoic Acid A, a Novel Sesquiterpenoid from the Formosan Gorgonian Coral Rumphella antipathies
title Rumphellaoic Acid A, a Novel Sesquiterpenoid from the Formosan Gorgonian Coral Rumphella antipathies
title_full Rumphellaoic Acid A, a Novel Sesquiterpenoid from the Formosan Gorgonian Coral Rumphella antipathies
title_fullStr Rumphellaoic Acid A, a Novel Sesquiterpenoid from the Formosan Gorgonian Coral Rumphella antipathies
title_full_unstemmed Rumphellaoic Acid A, a Novel Sesquiterpenoid from the Formosan Gorgonian Coral Rumphella antipathies
title_short Rumphellaoic Acid A, a Novel Sesquiterpenoid from the Formosan Gorgonian Coral Rumphella antipathies
title_sort rumphellaoic acid a, a novel sesquiterpenoid from the formosan gorgonian coral rumphella antipathies
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278205/
https://www.ncbi.nlm.nih.gov/pubmed/25486110
http://dx.doi.org/10.3390/md12125856
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