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Marine Pseudovibrio sp. as a Novel Source of Antimicrobials

Antibiotic resistance among pathogenic microorganisms is becoming ever more common. Unfortunately, the development of new antibiotics which may combat resistance has decreased. Recently, however the oceans and the marine animals that reside there have received increased attention as a potential sour...

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Detalles Bibliográficos
Autores principales: Crowley, Susan P., O’Gara, Fergal, O’Sullivan, Orla, Cotter, Paul D., Dobson, Alan D. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278209/
https://www.ncbi.nlm.nih.gov/pubmed/25501794
http://dx.doi.org/10.3390/md12125916
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author Crowley, Susan P.
O’Gara, Fergal
O’Sullivan, Orla
Cotter, Paul D.
Dobson, Alan D. W.
author_facet Crowley, Susan P.
O’Gara, Fergal
O’Sullivan, Orla
Cotter, Paul D.
Dobson, Alan D. W.
author_sort Crowley, Susan P.
collection PubMed
description Antibiotic resistance among pathogenic microorganisms is becoming ever more common. Unfortunately, the development of new antibiotics which may combat resistance has decreased. Recently, however the oceans and the marine animals that reside there have received increased attention as a potential source for natural product discovery. Many marine eukaryotes interact and form close associations with microorganisms that inhabit their surfaces, many of which can inhibit the attachment, growth or survival of competitor species. It is the bioactive compounds responsible for the inhibition that is of interest to researchers on the hunt for novel bioactives. The genus Pseudovibrio has been repeatedly identified from the bacterial communities isolated from marine surfaces. In addition, antimicrobial activity assays have demonstrated significant antimicrobial producing capabilities throughout the genus. This review will describe the potency, spectrum and possible novelty of the compounds produced by these bacteria, while highlighting the capacity for this genus to produce natural antimicrobial compounds which could be employed to control undesirable bacteria in the healthcare and food production sectors.
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spelling pubmed-42782092015-01-08 Marine Pseudovibrio sp. as a Novel Source of Antimicrobials Crowley, Susan P. O’Gara, Fergal O’Sullivan, Orla Cotter, Paul D. Dobson, Alan D. W. Mar Drugs Review Antibiotic resistance among pathogenic microorganisms is becoming ever more common. Unfortunately, the development of new antibiotics which may combat resistance has decreased. Recently, however the oceans and the marine animals that reside there have received increased attention as a potential source for natural product discovery. Many marine eukaryotes interact and form close associations with microorganisms that inhabit their surfaces, many of which can inhibit the attachment, growth or survival of competitor species. It is the bioactive compounds responsible for the inhibition that is of interest to researchers on the hunt for novel bioactives. The genus Pseudovibrio has been repeatedly identified from the bacterial communities isolated from marine surfaces. In addition, antimicrobial activity assays have demonstrated significant antimicrobial producing capabilities throughout the genus. This review will describe the potency, spectrum and possible novelty of the compounds produced by these bacteria, while highlighting the capacity for this genus to produce natural antimicrobial compounds which could be employed to control undesirable bacteria in the healthcare and food production sectors. MDPI 2014-12-09 /pmc/articles/PMC4278209/ /pubmed/25501794 http://dx.doi.org/10.3390/md12125916 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Crowley, Susan P.
O’Gara, Fergal
O’Sullivan, Orla
Cotter, Paul D.
Dobson, Alan D. W.
Marine Pseudovibrio sp. as a Novel Source of Antimicrobials
title Marine Pseudovibrio sp. as a Novel Source of Antimicrobials
title_full Marine Pseudovibrio sp. as a Novel Source of Antimicrobials
title_fullStr Marine Pseudovibrio sp. as a Novel Source of Antimicrobials
title_full_unstemmed Marine Pseudovibrio sp. as a Novel Source of Antimicrobials
title_short Marine Pseudovibrio sp. as a Novel Source of Antimicrobials
title_sort marine pseudovibrio sp. as a novel source of antimicrobials
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278209/
https://www.ncbi.nlm.nih.gov/pubmed/25501794
http://dx.doi.org/10.3390/md12125916
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