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Overcoming EMT-driven therapeutic resistance by BH3 mimetics

Epithelial-mesenchymal transition (EMT) contributes to the progression of cancer through enhanced invasion and stem-like properties of cancer cells. Additionally, EMT confers resistance towards many chemotherapeutics. We recently described a mechanism that mediates EMT-driven chemoresistance through...

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Detalles Bibliográficos
Autores principales:	Keitel, Ulrike, Scheel, Christina, Dobbelstein, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278270/ https://www.ncbi.nlm.nih.gov/pubmed/25593997

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