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Necroptosis is associated with low procaspase-8 and active RIPK1 and −3 in human glioma cells

Necroptosis is a regulated necrotic cell death that involves receptor-interacting protein kinases RIPK1 and RIPK3. Here, we report that edelfosine triggers a rapid and massive cell death in human glioblastoma cells with characteristics of necrosis. Only a minor proportion of edelfosine-treated cells...

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Detalles Bibliográficos
Autores principales:	Melo-Lima, Sara, Celeste Lopes, Maria, Mollinedo, Faustino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278276/ https://www.ncbi.nlm.nih.gov/pubmed/25593994

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