A novel role for the SUMO E3 ligase PIAS1 in cancer metastasis

Tumor metastasis contributes to the grave morbidity and mortality of cancer, but the mechanisms underlying tumor cell invasiveness and metastasis remain incompletely understood. Here, we report that expression of the SUMO E3 ligase PIAS1 suppresses TGFβ-induced activation of the matrix metalloprotei...

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Detalles Bibliográficos
Autores principales: Dadakhujaev, Shorafidinkhuja, Salazar-Arcila, Carolina, Netherton, Stuart J., Chandhoke, Amrita Singh, Singla, Arvind Kumar, Jirik, Frank R., Bonni, Shirin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278292/
https://www.ncbi.nlm.nih.gov/pubmed/25594015

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