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HER2 and HER3 cooperatively regulate cancer cell growth and determine sensitivity to the novel investigational EGFR/HER2 kinase inhibitor TAK-285
The human epidermal growth factor receptor (HER) family plays a major role in cancer cell proliferation. Overexpression of these receptors occurs in various cancers, including breast cancer, and correlates with shorter time to relapse and lower overall survival. We recently reported that TAK-285, an...
Autores principales: | Takagi, Shinji, Banno, Hiroshi, Hayashi, Akira, Tamura, Toshiya, Ishikawa, Tomoyasu, Ohta, Yoshikazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278294/ https://www.ncbi.nlm.nih.gov/pubmed/25594012 |
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