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Integrin αV modulates the cellular pharmacology of copper and cisplatin by regulating expression of the influx transporter CTR1

The αV integrin is expressed in most cancer cells where it regulates a diverse array of cellular functions essential to the initiation, progression and metastasis of solid tumors. However, little is known about how αV integrin modulates cellular sensitivity to chemotherapeutic agents, particularly t...

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Detalles Bibliográficos
Autores principales: Lin, Xinjian, Shang, Xiying, Manorek, Gerald, Fofana, Mariama, Stephen B., Howell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278295/
https://www.ncbi.nlm.nih.gov/pubmed/25594011