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BRCA1 and γH2AX as independent prognostic markers in oral squamous cell carcinoma
Oral squamous cell carcinomas (OSCC) are believed to originate from sequential mutations that can develop as a consequence of genetic instability acquired over time. BRCA1 are linked to DNA recombination and repair processes, being of importance for its role in regulation of RAD51 and H2AX (γH2AX)....
Autores principales: | Oliveira-Costa, Joao Paulo, Oliveira, Lucinei Roberto, Zanetti, Roberto, Zanetti, Juliana Silva, da Silveira, Giorgia Gobbi, Chavichiolli Buim, Marcilei Eliza, Zucoloto, Sergio, Ribeiro-Silva, Alfredo, Soares, Fernando Augusto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278309/ https://www.ncbi.nlm.nih.gov/pubmed/25594033 |
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