Clinical characteristics and outcomes of pediatric oncology patients with aggressive biology enrolled in phase I clinical trials designed for adults: The university of Texas MD Anderson cancer center experience

BACKGROUND: Children (patients ≤ 18 years of age) are not usually included on pharmaceutical industry sponsored Phase I trials. METHODS: We reviewed the medical records of 40 patients ≤ 18 years treated in ≥ 1 phase I trial at MD Anderson. RESULTS: The median OS was 8.5 months (95% CI, 5.5-13.2 mont...

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Detalles Bibliográficos
Autores principales: Corrales-Medina, Fernando F., Herzog, Cynthia, Hess, Kenneth, Egas-Bejar, Daniela, Hong, David S., Falchook, Gerald, Anderson, Pete, Nunez, Cesar, Huh, Winston W., Naing, Aung, Tsimberidou, Apostolia M., Wheler, Jennifer, Paul, Sarina Piha, Janku, Filip, Kleinerman, Eugenie S., Kurzrock, Razelle, Subbiah, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278323/
https://www.ncbi.nlm.nih.gov/pubmed/25587555

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