Pathways driving the endocytosis of mutant and wild-type EGFR in cancer

EGFR (epidermal growth factor receptor) is activated through changes in expression or mutations in a number of tumors and is a driving force in cancer progression. EGFR is targeted by numerous inhibitors, including chimeric antibodies targeting the extracellular domain and small molecule kinase doma...

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Detalles Bibliográficos
Autores principales: Hampton, Kaia K., Craven, Rolf J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278327/
https://www.ncbi.nlm.nih.gov/pubmed/25594057

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