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Enhancement of Mucosal Immunogenicity of Viral Vectored Vaccines by the NKT Cell Agonist Alpha-Galactosylceramide as Adjuvant
Gene-based vaccination strategies, specifically viral vectors encoding vaccine immunogens are effective at priming strong immune responses. Mucosal routes offer practical advantages for vaccination by ease of needle-free administration, and immunogen delivery at readily accessible oral/nasal sites t...
Autores principales: | Singh, Shailbala, Nehete, Pramod N., Yang, Guojun, He, Hong, Nehete, Bharti, Hanley, Patrick W., Barry, Michael A., Sastry, K. Jagannadha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278383/ https://www.ncbi.nlm.nih.gov/pubmed/25553254 http://dx.doi.org/10.3390/vaccines2040686 |
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