Cargando…
Genetic evidence for a pathogenic role for the vitamin D3 metabolizing enzyme CYP24A1 in multiple sclerosis()
BACKGROUND: Multiple sclerosis (MS) is a common disease of the central nervous system and a major cause of disability amongst young adults. Genome-wide association studies have identified many novel susceptibility loci including rs2248359. We hypothesized that genotypes of this locus could increase...
Autores principales: | Ramasamy, Adaikalavan, Trabzuni, Daniah, Forabosco, Paola, Smith, Colin, Walker, Robert, Dillman, Allissa, Sveinbjornsdottir, Sigurlaug, Hardy, John, Weale, Michael E., Ryten, Mina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B. V
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278441/ https://www.ncbi.nlm.nih.gov/pubmed/25568836 http://dx.doi.org/10.1016/j.msard.2013.08.009 |
Ejemplares similares
-
Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies
por: Trabzuni, Daniah, et al.
Publicado: (2011) -
Widespread sex differences in gene expression and splicing in the adult human brain
por: Trabzuni, Daniah, et al.
Publicado: (2013) -
Insights into TREM2 biology by network analysis of human brain gene expression data
por: Forabosco, Paola, et al.
Publicado: (2013) -
Resolving the polymorphism-in-probe problem is critical for correct interpretation of expression QTL studies
por: Ramasamy, Adaikalavan, et al.
Publicado: (2013) -
MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies
por: Trabzuni, Daniah, et al.
Publicado: (2012)