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Treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series
OBJECTIVE: To assess the efficacy and safety of the topical 5% lidocaine medicated plaster in the treatment of localized neuropathic pain. STUDY DESIGN: This was a case series at an Austrian pain clinic, using retrospective analysis. PATIENTS AND METHODS: Data of 27 patients treated for localized ne...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278790/ https://www.ncbi.nlm.nih.gov/pubmed/25565882 http://dx.doi.org/10.2147/IJGM.S74802 |
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author | Likar, Rudolf Demschar, Susanne Kager, Ingo Neuwersch, Stefan Pipam, Wolfgang Sittl, Reinhard |
author_facet | Likar, Rudolf Demschar, Susanne Kager, Ingo Neuwersch, Stefan Pipam, Wolfgang Sittl, Reinhard |
author_sort | Likar, Rudolf |
collection | PubMed |
description | OBJECTIVE: To assess the efficacy and safety of the topical 5% lidocaine medicated plaster in the treatment of localized neuropathic pain. STUDY DESIGN: This was a case series at an Austrian pain clinic, using retrospective analysis. PATIENTS AND METHODS: Data of 27 patients treated for localized neuropathic pain with the 5% lidocaine medicated plaster were retrospectively analyzed. Assessment included changes in overall pain intensity, in intensity of different pain qualities, and of hyperalgesia and allodynia, and changes in sleep quality. RESULTS: Patients (17 female, ten male; mean age 53.4±11.4 years) presented mainly with dorsalgia (16 patients) or postoperative/posttraumatic pain (seven patients); one patient suffered from both. The mean overall pain intensity prior to treatment with lidocaine medicated plaster was 8.4±1.2 on the 11-point Likert scale. In the majority of cases, the lidocaine plaster was applied concomitantly with preexisting pain medication (81.5% of the patients). During the 6-month observation period, overall mean pain intensity was reduced by almost 5 points (4.98) to 3.5±2.6. Substantial reductions were also observed for neuralgiform pain (5 points from 7.9±2.6 at baseline) and burning pain (3 points from 5.2±4.1). Sleep quality improved from 4.6±2.6 at baseline to 5.5±1.8. Stratification by pain diagnosis showed marked improvements in overall pain intensity for patients with dorsalgia or postoperative/posttraumatic pain. The lidocaine plaster was well tolerated. CONCLUSION: Overall, topical treatment with the 5% lidocaine medicated plaster was associated with effective pain relief and was well tolerated. |
format | Online Article Text |
id | pubmed-4278790 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-42787902015-01-06 Treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series Likar, Rudolf Demschar, Susanne Kager, Ingo Neuwersch, Stefan Pipam, Wolfgang Sittl, Reinhard Int J Gen Med Original Research OBJECTIVE: To assess the efficacy and safety of the topical 5% lidocaine medicated plaster in the treatment of localized neuropathic pain. STUDY DESIGN: This was a case series at an Austrian pain clinic, using retrospective analysis. PATIENTS AND METHODS: Data of 27 patients treated for localized neuropathic pain with the 5% lidocaine medicated plaster were retrospectively analyzed. Assessment included changes in overall pain intensity, in intensity of different pain qualities, and of hyperalgesia and allodynia, and changes in sleep quality. RESULTS: Patients (17 female, ten male; mean age 53.4±11.4 years) presented mainly with dorsalgia (16 patients) or postoperative/posttraumatic pain (seven patients); one patient suffered from both. The mean overall pain intensity prior to treatment with lidocaine medicated plaster was 8.4±1.2 on the 11-point Likert scale. In the majority of cases, the lidocaine plaster was applied concomitantly with preexisting pain medication (81.5% of the patients). During the 6-month observation period, overall mean pain intensity was reduced by almost 5 points (4.98) to 3.5±2.6. Substantial reductions were also observed for neuralgiform pain (5 points from 7.9±2.6 at baseline) and burning pain (3 points from 5.2±4.1). Sleep quality improved from 4.6±2.6 at baseline to 5.5±1.8. Stratification by pain diagnosis showed marked improvements in overall pain intensity for patients with dorsalgia or postoperative/posttraumatic pain. The lidocaine plaster was well tolerated. CONCLUSION: Overall, topical treatment with the 5% lidocaine medicated plaster was associated with effective pain relief and was well tolerated. Dove Medical Press 2014-12-19 /pmc/articles/PMC4278790/ /pubmed/25565882 http://dx.doi.org/10.2147/IJGM.S74802 Text en © 2015 Likar et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Likar, Rudolf Demschar, Susanne Kager, Ingo Neuwersch, Stefan Pipam, Wolfgang Sittl, Reinhard Treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series |
title | Treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series |
title_full | Treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series |
title_fullStr | Treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series |
title_full_unstemmed | Treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series |
title_short | Treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series |
title_sort | treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278790/ https://www.ncbi.nlm.nih.gov/pubmed/25565882 http://dx.doi.org/10.2147/IJGM.S74802 |
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