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Treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series

OBJECTIVE: To assess the efficacy and safety of the topical 5% lidocaine medicated plaster in the treatment of localized neuropathic pain. STUDY DESIGN: This was a case series at an Austrian pain clinic, using retrospective analysis. PATIENTS AND METHODS: Data of 27 patients treated for localized ne...

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Autores principales: Likar, Rudolf, Demschar, Susanne, Kager, Ingo, Neuwersch, Stefan, Pipam, Wolfgang, Sittl, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278790/
https://www.ncbi.nlm.nih.gov/pubmed/25565882
http://dx.doi.org/10.2147/IJGM.S74802
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author Likar, Rudolf
Demschar, Susanne
Kager, Ingo
Neuwersch, Stefan
Pipam, Wolfgang
Sittl, Reinhard
author_facet Likar, Rudolf
Demschar, Susanne
Kager, Ingo
Neuwersch, Stefan
Pipam, Wolfgang
Sittl, Reinhard
author_sort Likar, Rudolf
collection PubMed
description OBJECTIVE: To assess the efficacy and safety of the topical 5% lidocaine medicated plaster in the treatment of localized neuropathic pain. STUDY DESIGN: This was a case series at an Austrian pain clinic, using retrospective analysis. PATIENTS AND METHODS: Data of 27 patients treated for localized neuropathic pain with the 5% lidocaine medicated plaster were retrospectively analyzed. Assessment included changes in overall pain intensity, in intensity of different pain qualities, and of hyperalgesia and allodynia, and changes in sleep quality. RESULTS: Patients (17 female, ten male; mean age 53.4±11.4 years) presented mainly with dorsalgia (16 patients) or postoperative/posttraumatic pain (seven patients); one patient suffered from both. The mean overall pain intensity prior to treatment with lidocaine medicated plaster was 8.4±1.2 on the 11-point Likert scale. In the majority of cases, the lidocaine plaster was applied concomitantly with preexisting pain medication (81.5% of the patients). During the 6-month observation period, overall mean pain intensity was reduced by almost 5 points (4.98) to 3.5±2.6. Substantial reductions were also observed for neuralgiform pain (5 points from 7.9±2.6 at baseline) and burning pain (3 points from 5.2±4.1). Sleep quality improved from 4.6±2.6 at baseline to 5.5±1.8. Stratification by pain diagnosis showed marked improvements in overall pain intensity for patients with dorsalgia or postoperative/posttraumatic pain. The lidocaine plaster was well tolerated. CONCLUSION: Overall, topical treatment with the 5% lidocaine medicated plaster was associated with effective pain relief and was well tolerated.
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spelling pubmed-42787902015-01-06 Treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series Likar, Rudolf Demschar, Susanne Kager, Ingo Neuwersch, Stefan Pipam, Wolfgang Sittl, Reinhard Int J Gen Med Original Research OBJECTIVE: To assess the efficacy and safety of the topical 5% lidocaine medicated plaster in the treatment of localized neuropathic pain. STUDY DESIGN: This was a case series at an Austrian pain clinic, using retrospective analysis. PATIENTS AND METHODS: Data of 27 patients treated for localized neuropathic pain with the 5% lidocaine medicated plaster were retrospectively analyzed. Assessment included changes in overall pain intensity, in intensity of different pain qualities, and of hyperalgesia and allodynia, and changes in sleep quality. RESULTS: Patients (17 female, ten male; mean age 53.4±11.4 years) presented mainly with dorsalgia (16 patients) or postoperative/posttraumatic pain (seven patients); one patient suffered from both. The mean overall pain intensity prior to treatment with lidocaine medicated plaster was 8.4±1.2 on the 11-point Likert scale. In the majority of cases, the lidocaine plaster was applied concomitantly with preexisting pain medication (81.5% of the patients). During the 6-month observation period, overall mean pain intensity was reduced by almost 5 points (4.98) to 3.5±2.6. Substantial reductions were also observed for neuralgiform pain (5 points from 7.9±2.6 at baseline) and burning pain (3 points from 5.2±4.1). Sleep quality improved from 4.6±2.6 at baseline to 5.5±1.8. Stratification by pain diagnosis showed marked improvements in overall pain intensity for patients with dorsalgia or postoperative/posttraumatic pain. The lidocaine plaster was well tolerated. CONCLUSION: Overall, topical treatment with the 5% lidocaine medicated plaster was associated with effective pain relief and was well tolerated. Dove Medical Press 2014-12-19 /pmc/articles/PMC4278790/ /pubmed/25565882 http://dx.doi.org/10.2147/IJGM.S74802 Text en © 2015 Likar et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Likar, Rudolf
Demschar, Susanne
Kager, Ingo
Neuwersch, Stefan
Pipam, Wolfgang
Sittl, Reinhard
Treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series
title Treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series
title_full Treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series
title_fullStr Treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series
title_full_unstemmed Treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series
title_short Treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series
title_sort treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster – a case series
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278790/
https://www.ncbi.nlm.nih.gov/pubmed/25565882
http://dx.doi.org/10.2147/IJGM.S74802
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