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Recombinant Neuregulin 1 Does Not Activate Cardiomyocyte DNA Synthesis in Normal or Infarcted Adult Mice

OBJECTIVES: Neuregulin 1 signaling plays an important role in cardiac trabecular development, and in sustaining functional integrity in adult hearts. Treatment with neuregulin 1 enhances adult cardiomyocyte differentiation, survival and/or function in vitro and in vivo. It has also been suggested th...

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Detalles Bibliográficos
Autores principales: Reuter, Sean, Soonpaa, Mark H., Firulli, Anthony B., Chang, Audrey N., Field, Loren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278834/
https://www.ncbi.nlm.nih.gov/pubmed/25545368
http://dx.doi.org/10.1371/journal.pone.0115871