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Cdk1-Mediated Phosphorylation of Human ATF7 at Thr-51 and Thr-53 Promotes Cell-Cycle Progression into M Phase

Activating transcription factor 2 (ATF2) and its homolog ATF7 are phosphorylated at Thr-69/Thr-71 and at Thr-51/Thr-53, respectively, by stress-activated MAPKs regulating their transcriptional functions in G1 and S phases. However, little is known about the role of ATF2 and ATF7 in G2/M phase. Here,...

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Detalles Bibliográficos
Autores principales: Hasegawa, Hitomi, Ishibashi, Kenichi, Kubota, Shoichi, Yamaguchi, Chihiro, Yuki, Ryuzaburo, Nakajo, Haruna, Eckner, Richard, Yamaguchi, Noritaka, Yokoyama, Kazunari K., Yamaguchi, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278844/
https://www.ncbi.nlm.nih.gov/pubmed/25545367
http://dx.doi.org/10.1371/journal.pone.0116048