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Nerve Growth Factor Protects the Ischemic Heart via Attenuation of the Endoplasmic Reticulum Stress Induced Apoptosis by Activation of Phosphatidylinositol 3-Kinase

Background: Increased expression of nerve growth factor (NGF) has been found in the myocardium suffered from ischemia and reperfusion (I/R). The pro-survival activity of NGF on ischemic heart has been supposed to be mediated by phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) signaling path...

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Detalles Bibliográficos
Autores principales: Wei, Ke, Liu, Li, Xie, Fei, Hao, Xuechao, Luo, Jie, Min, Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278880/
https://www.ncbi.nlm.nih.gov/pubmed/25552923
http://dx.doi.org/10.7150/ijms.10101