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Cancer: We Should Not Forget The Past
Cancer has been in existence longer than human beings, and man has been facing the illness ever since he made his appearance on Earth. Amazingly, the first human cancer gene was cloned only thirty years ago. This, and other extraordinary scientific goals achieved by molecular cancer research in the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278912/ https://www.ncbi.nlm.nih.gov/pubmed/25553086 http://dx.doi.org/10.7150/jca.10336 |
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author | Di Lonardo, Anna Nasi, Sergio Pulciani, Simonetta |
author_facet | Di Lonardo, Anna Nasi, Sergio Pulciani, Simonetta |
author_sort | Di Lonardo, Anna |
collection | PubMed |
description | Cancer has been in existence longer than human beings, and man has been facing the illness ever since he made his appearance on Earth. Amazingly, the first human cancer gene was cloned only thirty years ago. This, and other extraordinary scientific goals achieved by molecular cancer research in the last 30 years, seems to suggest that definitive answers and solutions to this severe disease have been finally found. This was not the case, as cancer still remains to be defeated. To do so, cancer must be first understood. This review highlights how cancer onset and progression has been tackled from ancient times to present day. Old theories and achievements have provided the pillars of cancer understanding, in laying the basis of 'modern era' cancer research, are discussed. The review highlights the discovery of oncogenes and suppressor tumor genes, underlining the crucial role of these achievements in cancer diagnosis and therapies. Finally, an overview of how the modern technologies have given impetuous to expedite these goals is also considered. |
format | Online Article Text |
id | pubmed-4278912 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Ivyspring International Publisher |
record_format | MEDLINE/PubMed |
spelling | pubmed-42789122015-01-01 Cancer: We Should Not Forget The Past Di Lonardo, Anna Nasi, Sergio Pulciani, Simonetta J Cancer Review Cancer has been in existence longer than human beings, and man has been facing the illness ever since he made his appearance on Earth. Amazingly, the first human cancer gene was cloned only thirty years ago. This, and other extraordinary scientific goals achieved by molecular cancer research in the last 30 years, seems to suggest that definitive answers and solutions to this severe disease have been finally found. This was not the case, as cancer still remains to be defeated. To do so, cancer must be first understood. This review highlights how cancer onset and progression has been tackled from ancient times to present day. Old theories and achievements have provided the pillars of cancer understanding, in laying the basis of 'modern era' cancer research, are discussed. The review highlights the discovery of oncogenes and suppressor tumor genes, underlining the crucial role of these achievements in cancer diagnosis and therapies. Finally, an overview of how the modern technologies have given impetuous to expedite these goals is also considered. Ivyspring International Publisher 2015-01-01 /pmc/articles/PMC4278912/ /pubmed/25553086 http://dx.doi.org/10.7150/jca.10336 Text en © Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited. |
spellingShingle | Review Di Lonardo, Anna Nasi, Sergio Pulciani, Simonetta Cancer: We Should Not Forget The Past |
title | Cancer: We Should Not Forget The Past |
title_full | Cancer: We Should Not Forget The Past |
title_fullStr | Cancer: We Should Not Forget The Past |
title_full_unstemmed | Cancer: We Should Not Forget The Past |
title_short | Cancer: We Should Not Forget The Past |
title_sort | cancer: we should not forget the past |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278912/ https://www.ncbi.nlm.nih.gov/pubmed/25553086 http://dx.doi.org/10.7150/jca.10336 |
work_keys_str_mv | AT dilonardoanna cancerweshouldnotforgetthepast AT nasisergio cancerweshouldnotforgetthepast AT pulcianisimonetta cancerweshouldnotforgetthepast |