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Cancer: We Should Not Forget The Past

Cancer has been in existence longer than human beings, and man has been facing the illness ever since he made his appearance on Earth. Amazingly, the first human cancer gene was cloned only thirty years ago. This, and other extraordinary scientific goals achieved by molecular cancer research in the...

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Detalles Bibliográficos
Autores principales: Di Lonardo, Anna, Nasi, Sergio, Pulciani, Simonetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278912/
https://www.ncbi.nlm.nih.gov/pubmed/25553086
http://dx.doi.org/10.7150/jca.10336
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author Di Lonardo, Anna
Nasi, Sergio
Pulciani, Simonetta
author_facet Di Lonardo, Anna
Nasi, Sergio
Pulciani, Simonetta
author_sort Di Lonardo, Anna
collection PubMed
description Cancer has been in existence longer than human beings, and man has been facing the illness ever since he made his appearance on Earth. Amazingly, the first human cancer gene was cloned only thirty years ago. This, and other extraordinary scientific goals achieved by molecular cancer research in the last 30 years, seems to suggest that definitive answers and solutions to this severe disease have been finally found. This was not the case, as cancer still remains to be defeated. To do so, cancer must be first understood. This review highlights how cancer onset and progression has been tackled from ancient times to present day. Old theories and achievements have provided the pillars of cancer understanding, in laying the basis of 'modern era' cancer research, are discussed. The review highlights the discovery of oncogenes and suppressor tumor genes, underlining the crucial role of these achievements in cancer diagnosis and therapies. Finally, an overview of how the modern technologies have given impetuous to expedite these goals is also considered.
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spelling pubmed-42789122015-01-01 Cancer: We Should Not Forget The Past Di Lonardo, Anna Nasi, Sergio Pulciani, Simonetta J Cancer Review Cancer has been in existence longer than human beings, and man has been facing the illness ever since he made his appearance on Earth. Amazingly, the first human cancer gene was cloned only thirty years ago. This, and other extraordinary scientific goals achieved by molecular cancer research in the last 30 years, seems to suggest that definitive answers and solutions to this severe disease have been finally found. This was not the case, as cancer still remains to be defeated. To do so, cancer must be first understood. This review highlights how cancer onset and progression has been tackled from ancient times to present day. Old theories and achievements have provided the pillars of cancer understanding, in laying the basis of 'modern era' cancer research, are discussed. The review highlights the discovery of oncogenes and suppressor tumor genes, underlining the crucial role of these achievements in cancer diagnosis and therapies. Finally, an overview of how the modern technologies have given impetuous to expedite these goals is also considered. Ivyspring International Publisher 2015-01-01 /pmc/articles/PMC4278912/ /pubmed/25553086 http://dx.doi.org/10.7150/jca.10336 Text en © Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.
spellingShingle Review
Di Lonardo, Anna
Nasi, Sergio
Pulciani, Simonetta
Cancer: We Should Not Forget The Past
title Cancer: We Should Not Forget The Past
title_full Cancer: We Should Not Forget The Past
title_fullStr Cancer: We Should Not Forget The Past
title_full_unstemmed Cancer: We Should Not Forget The Past
title_short Cancer: We Should Not Forget The Past
title_sort cancer: we should not forget the past
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278912/
https://www.ncbi.nlm.nih.gov/pubmed/25553086
http://dx.doi.org/10.7150/jca.10336
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