Disease Caused by Rotavirus Infection

Although rotavirus vaccines are available, rotaviruses remain the major cause of childhood diarrheal disease worldwide. The Rotarix (GlaxoSmithKline Biologicals Rixensart, Belgium) and RotaTeq (Merck and Co., Inc. Whitehouse Station, New Jersey, USA) vaccines are effective for reducing the morbidity...

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Detalles Bibliográficos
Autores principales: Lin, Che-Liang, Chen, Shou-Chien, Liu, Shyun-Yeu, Chen, Kow-Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279035/
https://www.ncbi.nlm.nih.gov/pubmed/25553142
http://dx.doi.org/10.2174/1874357901408010014
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author Lin, Che-Liang
Chen, Shou-Chien
Liu, Shyun-Yeu
Chen, Kow-Tong
author_facet Lin, Che-Liang
Chen, Shou-Chien
Liu, Shyun-Yeu
Chen, Kow-Tong
author_sort Lin, Che-Liang
collection PubMed
description Although rotavirus vaccines are available, rotaviruses remain the major cause of childhood diarrheal disease worldwide. The Rotarix (GlaxoSmithKline Biologicals Rixensart, Belgium) and RotaTeq (Merck and Co., Inc. Whitehouse Station, New Jersey, USA) vaccines are effective for reducing the morbidity and mortality of rotavirus infection. This article aims to assess the epidemiology of rotaviral gastroenteritis and the efficacy and effectiveness of licensed rotavirus vaccines. This review concludes by presenting challenges in the field that require further exploration by and perspectives from basic and translational research in the future.
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spelling pubmed-42790352014-12-31 Disease Caused by Rotavirus Infection Lin, Che-Liang Chen, Shou-Chien Liu, Shyun-Yeu Chen, Kow-Tong Open Virol J Article Although rotavirus vaccines are available, rotaviruses remain the major cause of childhood diarrheal disease worldwide. The Rotarix (GlaxoSmithKline Biologicals Rixensart, Belgium) and RotaTeq (Merck and Co., Inc. Whitehouse Station, New Jersey, USA) vaccines are effective for reducing the morbidity and mortality of rotavirus infection. This article aims to assess the epidemiology of rotaviral gastroenteritis and the efficacy and effectiveness of licensed rotavirus vaccines. This review concludes by presenting challenges in the field that require further exploration by and perspectives from basic and translational research in the future. Bentham Open 2014-12-11 /pmc/articles/PMC4279035/ /pubmed/25553142 http://dx.doi.org/10.2174/1874357901408010014 Text en © Lin et al.; Licensee Bentham Open. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Lin, Che-Liang
Chen, Shou-Chien
Liu, Shyun-Yeu
Chen, Kow-Tong
Disease Caused by Rotavirus Infection
title Disease Caused by Rotavirus Infection
title_full Disease Caused by Rotavirus Infection
title_fullStr Disease Caused by Rotavirus Infection
title_full_unstemmed Disease Caused by Rotavirus Infection
title_short Disease Caused by Rotavirus Infection
title_sort disease caused by rotavirus infection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279035/
https://www.ncbi.nlm.nih.gov/pubmed/25553142
http://dx.doi.org/10.2174/1874357901408010014
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