Cargando…

Treating type-1 diabetes with an epigenetic drug

A single drug treats type-1 diabetes in mice by dampening inflammation and enhancing insulin production.

Detalles Bibliográficos
Autores principales:	Kitagawa, Yohko, Ohkura, Naganari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279079/ https://www.ncbi.nlm.nih.gov/pubmed/25549298 http://dx.doi.org/10.7554/eLife.05720

Ejemplares similares

Molecular Determinants of Regulatory T Cell Development: The Essential Roles of Epigenetic Changes
por: Kitagawa, Yohko, et al.
Publicado: (2013)

Dynamic Imprinting of the Treg Cell-Specific Epigenetic Signature in Developing Thymic Regulatory T Cells
por: Herppich, Susanne, et al.
Publicado: (2019)

Transcriptional and epigenetic basis of Treg cell development and function: its genetic anomalies or variations in autoimmune diseases
por: Ohkura, Naganari, et al.
Publicado: (2020)

Functional Roles of the IgM Fc Receptor in the Immune System
por: Kubagawa, Hiromi, et al.
Publicado: (2019)

Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
por: Mikami, Norihisa, et al.
Publicado: (2020)

Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells
por: Garg, Garima, et al.
Publicado: (2017)

Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells
por: Fu, Wenxian, et al.
Publicado: (2014)

Identification of the novel FOXP3-dependent T(reg) cell transcription factor MEOX1 by high-dimensional analysis of human CD4(+) T cells
por: Baßler, Kevin, et al.
Publicado: (2023)

VIRTUS: a pipeline for comprehensive virus analysis from conventional RNA-seq data
por: Yasumizu, Yoshiaki, et al.
Publicado: (2020)

Inflammation-Related Epigenetic Modification: The Bridge Between Immune and Metabolism in Type 2 Diabetes
por: Ding, Qiyou, et al.
Publicado: (2022)

Epigenetic Modifiers: Anti-Neoplastic Drugs With Immunomodulating Potential
por: Maes, Ken, et al.
Publicado: (2021)

Epigenetics and endoplasmic reticulum in podocytopathy during diabetic nephropathy progression
por: Wang, Xiaokang, et al.
Publicado: (2022)

Epigenetically altered macrophages promote development of diabetes-associated atherosclerosis
por: Huang, Dong, et al.
Publicado: (2023)

Immunotherapy With Human Gamma Delta T Cells—Synergistic Potential of Epigenetic Drugs?
por: Bhat, Jaydeep, et al.
Publicado: (2018)

Inflammasomes and Type 1 Diabetes
por: Pearson, James Alexander, et al.
Publicado: (2021)

Childhood Vaccinations and Type 1 Diabetes
por: Esposito, Susanna, et al.
Publicado: (2021)

Chemokines in Type 1 Diabetes Mellitus
por: Pan, Xiongfeng, et al.
Publicado: (2022)

Editorial: Immunopathology of Type 1 Diabetes
por: Green, E. Allison, et al.
Publicado: (2022)

Epigenetic control of type III interferon expression by 8-oxoguanine and its reader 8-oxoguanine DNA glycosylase1
por: Xue, Yaoyao, et al.
Publicado: (2023)

Hematopoietic Stem Cells in Type 1 Diabetes
por: Pastore, Ida, et al.
Publicado: (2021)

Extracellular Vesicle Therapy for Type 1 Diabetes
por: Soltani, Setareh, et al.
Publicado: (2022)

Monitoring immunomodulation strategies in type 1 diabetes
por: Krishnamurthy, Balasubramanian, et al.
Publicado: (2023)

Microbiota Inhibit Epithelial Pathogen Adherence by Epigenetically Regulating C-Type Lectin Expression
por: Woo, Vivienne, et al.
Publicado: (2019)

Variable frequencies of peripheral T-lymphocyte subsets in the diabetes spectrum from type 1 diabetes through latent autoimmune diabetes in adults (LADA) to type 2 diabetes
por: Tan, Tingting, et al.
Publicado: (2022)

The Role of Epigenetics in Type 1 Diabetes
por: Jerram, Samuel T., et al.
Publicado: (2017)

Peptide Immunotherapy for Type 1 Diabetes—Clinical Advances
por: Smith, Emma L., et al.
Publicado: (2018)

Evolving Antibody Therapies for the Treatment of Type 1 Diabetes
por: Ke, Qi, et al.
Publicado: (2021)

Regulatory B Cells: Role in Type 1 Diabetes
por: Boldison, Joanne, et al.
Publicado: (2021)

Identification of Sorafenib as a Treatment for Type 1 Diabetes
por: Zeng, Qin, et al.
Publicado: (2022)

The Role of Heat Shock Proteins in Type 1 Diabetes
por: Moin, Abu Saleh Md, et al.
Publicado: (2021)

The Contribution of Neutrophils and NETs to the Development of Type 1 Diabetes
por: Petrelli, Alessandra, et al.
Publicado: (2022)

Leverage biomaterials to modulate immunity for type 1 diabetes
por: Jing, Zhangyan, et al.
Publicado: (2022)

PPARs at the crossroads of T cell differentiation and type 1 diabetes
por: Riaz, Farooq, et al.
Publicado: (2023)

Type-I Interferons Inhibit Interleukin-10 Signaling and Favor Type 1 Diabetes Development in Nonobese Diabetic Mice
por: Iglesias, Marcos, et al.
Publicado: (2018)

Epigenetic regulation of HGK/MAP4K4 in T cells of type 2 diabetes patients
por: Chuang, Huai-Chia, et al.
Publicado: (2016)

Cell Polarization and Epigenetic Status Shape the Heterogeneous Response to Type III Interferons in Intestinal Epithelial Cells
por: Bhushal, Sudeep, et al.
Publicado: (2017)

Epigenetic Regulation in Kidney Transplantation
por: Xiang, Xiaohong, et al.
Publicado: (2022)

Editorial: Epigenetics of infectious diseases
por: Kulkarni, Smita, et al.
Publicado: (2022)

Dendritic Cell Subsets in Type 1 Diabetes: Friend or Foe?
por: Morel, Penelope A.
Publicado: (2013)

Approaches in Immunotherapy, Regenerative Medicine, and Bioengineering for Type 1 Diabetes
por: Kopan, Christopher, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_9dfo8g1hn6cgjd842fg0the7er