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Biology of IL-27 and its Role in the Host Immunity against Mycobacterium Tuberculosis

IL-27, a heterodimeric cytokine of IL-12 family, regulates both innate and adaptive immunity largely via Jak-Stat signaling. IL-27 can induce IFN-γ and inflammatory mediators from T lymphocytes and innate immune cells. IL-27 has unique anti-inflammatory properties via both Tr1 cells dependent and in...

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Detalles Bibliográficos
Autores principales:	Abdalla, Abualgasim Elgaili, Li, Qiming, Xie, Longxiang, Xie, Jianping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279092/ https://www.ncbi.nlm.nih.gov/pubmed/25561899 http://dx.doi.org/10.7150/ijbs.10464

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